1602935-10-3Relevant academic research and scientific papers
CuBr-promoted formal hydroacylation of 1-alkynes with glyoxal derivatives: An unexpected synthesis of 1,2-dicarbonyl-3-enes
Chen, Shufeng,Li, Xiaojie,Zhao, Haiying,Li, Baoguo
, p. 4137 - 4141 (2014)
An efficient and concise protocol has been developed for the highly regio- and stereoselective synthesis of E-1,2-dicarbonyl-3-ene derivatives by a copper-promoted reaction of 1-alkynes with α-carbonyl aldehydes in the presence of morpholine. The products obtained are believed as the formal hydroacylation of the triple bond.
