160308-12-3

Upstream product

• 1824-96-0 methyl ribofuranoside 
• 98-88-4 benzoyl chloride 
• 14233-62-6 2,3,5-tri-O-benzyl-1-deoxy-D-ribofuranose 
• 313484-66-1 (3R,4R,5R)-2-Methoxy-3,4-bis-trimethylsilanyloxy-5-trimethylsilanyloxymethyl-tetrahydro-furan 
• 149097-60-9 1,4-anhydro-2-amino-2-deoxy-3,5-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-D-arabinitol 
• 160308-05-4 3,5-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-1-deoxy-D-ribofuranose 
• 160308-07-6 1,4-anhydro-2-azido-2-deoxy-3,5-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-D-arabinitol 
• 160308-06-5 1,4-anhydro-2-O-methanesulfonyl-3,5-O-(1,1,3,3-tetraisopropyl-1,3-disiloxanediyl)-D-ribitol 
• 259137-72-9 Benzoic acid (2R,3S,4R)-4-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-3-hydroxy-tetrahydro-furan-2-ylmethyl ester 
• 64332-73-6 1,4-anhydro-2-deoxy-2-<3,4-dihydro-2,4-dioxo-1(2H)-pyrimidinyl>-D-arabinitol 
• 491-19-0 1,4-anhydro-D-ribitol 

Downstream Products

• 160308-13-4 1,4-anhydro-5-O-benzoyl-2-deoxy-2-<3,4-dihydro-4-oxo-1(2H)-pyrimidinyl>-D-lyxitol 

Relevant academic research and scientific papers

Synthesis of isonucleosides related to AZT and AZU

Approaches to 1,4-anhydro-3-azido-2,3-dideoxy-2-[3,4-dihydro-2,4-dioxo-5- methyl-1(2H)-pyrimidinyl]-D-arabinitol, and the related uracil derivative, have been developed. These conceptually new, optically active analogs of AZT, derived from 1,4-anhydro-D-ribitol, are among the first examples of regioisomeric analogs of AZT.