160318-86-5Relevant academic research and scientific papers
Gold-catalyzed synthesis of functionalized pyridines by using 2H-azirines as synthetic equivalents of alkenyl nitrenes
Prechter, Agnes,Henrion, Guilhem,Faudot Dit Bel, Pierre,Gagosz, Fabien
supporting information, p. 4959 - 4963 (2014/05/20)
2H-Azirines are easily synthesized from the corresponding ketones and, despite possessing a C=N bond embedded in a strained three-membered cycle, they are sufficiently stable to be isolated, stored, and manipulated. 2H-Azirines can be regarded as valuable
Synthesis of pyridines by carbenoid-mediated ring opening of 2H-azirines
Loy, Nicole S. Y.,Singh, Alok,Xu, Xianxiu,Park, Cheol-Min
supporting information, p. 2212 - 2216 (2013/04/10)
Roaming the range: The title reaction tolerates a wide range of substituents on the resulting pyridine ring using mild reaction conditions (see scheme; esp=α,α,α′,α′-tetramethyl-1,3- benzenedipropionic acid). The formation of the key intermediate is catal
Titanium-catalyzed Reformatsky-type reaction
Sgreccia, Laura,Bandini, Marco,Morganti, Stefano,Quintavalla, Arianna,Umani-Ronchi, Achille,Cozzi, Pier Giorgio
, p. 3191 - 3197 (2008/02/08)
A catalytic titanium mediated Reformatsky reaction is presented. The technique employs cyclopentadienyltitaniumdichloride(IV) (10 mol%) in conjunction with Mn (2 equiv.), as the stoichiometric reductant, and (CF3CO)2O (1.5 equiv.), a
