16036-21-8Relevant articles and documents
1,4,2-Dioxazol-5-ones as Isocyanate Equivalents: Chemoselective Non-Metal-Catalyzed Carboxamidation of Indoles
Vala, Anand,Parmar, Deepa,Rayani, Rahul,Kusurkar, Rakesh,Guduru, Ramakrishna,Kaneriya, Uttam,Gondaliya, Uday,Parmar, Nirali,Soni, Jigar Y.
, (2022/02/21)
1,4,2-Dioxazol-5-ones are known to undergo decarboxylation under thermal conditions followed by Lossen s rearrangement to give isocyanates. Described herein is the in situ trapping of the isocyanates by indoles to give indole-3-carboxamides in good to exc
Highly stereoselective ruthenium(II)-catalyzed direct C2- syn -alkenylation of indoles with alkynes
Zhang, Wei,Wei, Jun,Fu, Shaomin,Lin, Dongen,Jiang, Huanfeng,Zeng, Wei
supporting information, p. 1349 - 1352 (2015/03/30)
A carboamide-directed ruthenium-catalyzed C2-hydroindolation of alkynes has been described. This transformation provides a rapid access to free (N-H) C2-syn-alkenylated indole derivatives with the assistance of copper(II) salts, in which the directing group is removed via a one-pot process.
AlMe3-mediated regio- and chemoselective reactions of indole with carbamoyl electrophiles
Velavan,Sumathi,Balasubramanian
, p. 3148 - 3157 (2013/06/27)
Herein, we report the regio- and chemoselective reactions of indole with carbamoyl electrophiles in presence of AlMe3. Indole-3-carboxamide was prepared in one-step from a reaction of indole with tertiary carbamoylimidazole in the presence AlMe