33876-94-7

Basic information

• Product Name: 1H-Imidazole-1-carboxamide, N-phenyl-
• CAS NO: 33876-94-7
• Molecular Formula: C10H9N3O
• Molecular Weight: 187.201
• Mol File: 33876-94-7.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole-1-carboxamide, N-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole-1-carboxamide, N-phenyl-(33876-94-7)
• EPA Substance Registry System: 1H-Imidazole-1-carboxamide, N-phenyl-(33876-94-7)

Safety Data

• Hazardous Substances Data: 33876-94-7(Hazardous Substances Data)

Upstream product

• 288-32-4 1H-imidazole 
• 4910-32-1 1,3-diphenylcarbamothioate 
• 103-71-9 phenyl isocyanate 
• 18156-74-6 1-(Trimethylsilyl)imidazole 
• 62-53-3 aniline 
• 530-62-1 1,1'-carbonyldiimidazole 

Downstream Products

• 288-32-4 1H-imidazole 
• 103-71-9 phenyl isocyanate 
• 1467-21-6 N-phenyl-N'-benzylurea 
• 4930-03-4 phenyl N-phenylcarbamate 
• 1201-15-6 3-methyl-1-phenylimidazol-2(1H)-one 
• 100-61-8 N-methylaniline 
• 1461-81-0 N,N-diisopropyl-N'-phenylurea 
• 4559-92-6 N-phenylmorpholine-4-carboxamide 
• 886-59-9 N-cyclohexyl-N'-phenylurea 
• 75735-35-2 1-(N-phenylformimidoyl)imidazole 
• 16036-21-8 N-phenyl-1H-indole-1-carboxamide 
• 1035558-36-1 1-{4-[2-(3-hydroxy-propylamino)-pyrimidin-4-yloxy]-phenyl}-3-phenyl-urea 
• 103-70-8 Formanilid 

Relevant articles and documents

A facile method for the preparation of unsymmetrical ureas utilizing zirconium (IV) chloride

A facile synthetic method for the preparation of unsymmetrical ureas from amines is described. Carbamoyl imidazole compounds were prepared by the reaction of 1, 1-carbonyldiimidazole with primary or secondary amines, and further activation by treatment with zirconium(IV) chloride to generate the desired urea. This reaction protocol was applied to the synthesis of tri and tetrasubstituted ureas with high yields. This study provides an alternative guideline for the practical preparation of various unsymmetrical ureas.

Antidepressant activity of carbamates and urea derivatives

Thirteen (13) compounds of N-phenyl-O-alkyl carbamates (1 and 3), N,N-diethyl-N′-alkyl/aryl/phenylpiperazinoureas (4-6, 8-12), N-phenyl-N′-phenylpiperazino/imidazoureas (2, 7), and N-ethyl-(N′- phenylpiperazino) thioureas 13 were synthesized and tested for their antidepressant-like activity in mice. It was found that compound N-phenyl-O-heptyl carbamate 1 and N-phenyl-N′-phenylpiperazinourea 2 showed 32.5 and 27.7% antidepressant activity in the forced swim test in mice, respectively. Considering other carbamates it was found that a decrease in alkyl chain length caused a marked decline in the antidepressant activity. Compounds 1-4 show even higher activities in the forced swim test than the standard phenelzine. Springer Science+Business Media, LLC 2011.

Sulfuric acid-promoted rearrangement of 3-(N-acylamino)-substituted caran-4-one oximes

The rearrangement of 3-(N-acylamino)-substituted caran-4-one oximes in the presence of sulfuric acid affords 2-oxa-4-azabicyclo[3.3.1]non-3-en-6-one derivatives. 3-Aminocaran-4-one oximes, in which the amino group contains such substituents as acetyl, pro