1603829-79-3Relevant academic research and scientific papers
SMALL MOLECULE ANALOGS OF THE PROTEIN E4ORF1 IN THE TREATMENT AND PREVENTION OF METABOLIC DISORDERS
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Paragraph 00100; 00102, (2020/07/25)
In an embodiment, the present disclosure pertains to compositions and methods for modulating cellular glucose uptake. In general, the methods include associating cells with the compositions of the present disclosure. In another aspect, the present disclos
COMPOSITIONS AND METHODS FOR IMPROVING GLUCOSE UPTAKE
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Paragraph 0091, (2014/05/07)
A compound includes the structure of general Formula (II), pharmaceutically acceptable salts thereof, and/or solvates thereof: wherein R1, R2, R3, are independently selected from the group consisting of null, hydroxy, alkoxy, and halo, or R1 and R2 taken together form a cyclic boronate ester and R3 is null; wherein when four bonds to boron are present, boron bears a formal negative charge and the structure further comprises a countercation that is potassium or sodium,X1, X2, X3, and X4 are independently selected from the group consisting of O, CH, and N, with the proviso that no more than two of combined O and N are selected, and Z is selected from the group consisting of hydrogen, alkyl, aryl, heteroaryl, and halogen, any of which may be optionally substituted. Such compounds can increase glucose uptake by cells and preferably do not substantially increase adipogenesis.
