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160384-37-2

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160384-37-2 Usage

Description

3-[4-[2-(2,5-Dichloro-4-nitrophenyl)ethenyl]-1-piperazinyl]-1,2-benzisothiazole is a complex organic compound characterized by its red solid appearance. It is an intermediate in the synthesis of the antipsychotic agent Ziprasidone (Z485000), which highlights its significance in the pharmaceutical industry.

Uses

Used in Pharmaceutical Industry:
3-[4-[2-(2,5-Dichloro-4-nitrophenyl)ethenyl]-1-piperazinyl]-1,2-benzisothiazole is used as an intermediate in the synthesis of antipsychotic agents, specifically for the production of Ziprasidone (Z485000). Its role in the development of this medication is crucial, as it contributes to the treatment of various psychiatric disorders and conditions.
As an intermediate in the synthesis of antipsychotic agents, 3-[4-[2-(2,5-Dichloro-4-nitrophenyl)ethenyl]-1-piperazinyl]-1,2-benzisothiazole plays a vital role in the pharmaceutical industry. Its chemical properties and structure enable the creation of effective medications that can help manage and treat mental health conditions. The compound's red solid form also provides a distinctive characteristic that can be useful in identifying and handling it during the synthesis process.

Check Digit Verification of cas no

The CAS Registry Mumber 160384-37-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,0,3,8 and 4 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 160384-37:
(8*1)+(7*6)+(6*0)+(5*3)+(4*8)+(3*4)+(2*3)+(1*7)=122
122 % 10 = 2
So 160384-37-2 is a valid CAS Registry Number.

160384-37-2Downstream Products

160384-37-2Relevant articles and documents

A novel synthesis of the antipsychotic agent ziprasidone

Urban, Frank J.,Breitenbach, Ralph,Gonyaw, Dianne

, p. 1629 - 1638 (2007/10/03)

A new synthesis of the antipsychotic ziprasidone from 2,5-dichloro-4-nitrotoluene 3 is presented. The nitro group in 3 was used to activate the orthochlorine for displacement and the methyl group for enamine formation and introduction of the piperazinyl moiety.

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