1603845-32-4 Usage
Uses
TX 1-85-1 is the first selective Her3 ligand, forms a covalent bond with Cys721 located in the ATP-binding site of Her3.
Check Digit Verification of cas no
The CAS Registry Mumber 1603845-32-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,0,3,8,4 and 5 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1603845-32:
(9*1)+(8*6)+(7*0)+(6*3)+(5*8)+(4*4)+(3*5)+(2*3)+(1*2)=154
154 % 10 = 4
So 1603845-32-4 is a valid CAS Registry Number.
1603845-32-4Relevant articles and documents
Development of small molecules targeting the pseudokinase Her3
Lim, Sang Min,Xie, Ting,Westover, Kenneth D.,Ficarro, Scott B.,Tae, Hyun Seop,Gurbani, Deepak,Sim, Taebo,Marto, Jarrod A.,J?nne, Pasi A.,Crews, Craig M.,Gray, Nathanael S.
, p. 3382 - 3389 (2015/07/08)
Abstract Her3 is a member of the human epidermal growth factor receptor (EGFR) tyrosine kinase family, and it is often either overexpressed or deregulated in many types of human cancer. Her3 has not been the subject of small-molecule inhibitor development