1603845-32-4 Usage
Uses
Used in Pharmaceutical Industry:
TX-85-1 is used as a selective Her3 ligand for targeting the ATP-binding site of Her3. This selective interaction can be utilized in the development of drugs that modulate Her3 activity, which may have implications in the treatment of certain cancers and other diseases where Her3 plays a significant role.
Used in Drug Development:
TX-85-1 is used as a research tool for studying the structure and function of Her3 and its role in cellular processes. This understanding can aid in the development of targeted therapies that exploit the unique properties of TX-85-1 to disrupt or modulate Her3 activity.
Used in Cancer Research:
TX-85-1 is used as a compound for investigating the role of Her3 in cancer progression and resistance to existing treatments. By selectively targeting Her3, researchers can gain insights into the potential of TX-85-1 as a therapeutic agent in the treatment of various types of cancer.
Used in Biochemical Studies:
TX-85-1 is used as a reagent in biochemical experiments to study the interactions between Her3 and other cellular components. This can provide valuable information on the molecular mechanisms underlying Her3's role in cellular processes and its potential as a therapeutic target.
Check Digit Verification of cas no
The CAS Registry Mumber 1603845-32-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,6,0,3,8,4 and 5 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1603845-32:
(9*1)+(8*6)+(7*0)+(6*3)+(5*8)+(4*4)+(3*5)+(2*3)+(1*2)=154
154 % 10 = 4
So 1603845-32-4 is a valid CAS Registry Number.
1603845-32-4Relevant academic research and scientific papers
Development of small molecules targeting the pseudokinase Her3
Lim, Sang Min,Xie, Ting,Westover, Kenneth D.,Ficarro, Scott B.,Tae, Hyun Seop,Gurbani, Deepak,Sim, Taebo,Marto, Jarrod A.,J?nne, Pasi A.,Crews, Craig M.,Gray, Nathanael S.
, p. 3382 - 3389 (2015/07/08)
Abstract Her3 is a member of the human epidermal growth factor receptor (EGFR) tyrosine kinase family, and it is often either overexpressed or deregulated in many types of human cancer. Her3 has not been the subject of small-molecule inhibitor development
