160388-56-7

Basic information

• Product Name: [4-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]METHANOL
• Synonyms: [4-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]METHANOL
• CAS NO: 160388-56-7
• Molecular Formula: C₁₀H₁₁N₃O
• Molecular Weight: 189.21
• Mol File: 160388-56-7.mol
• Article Data: 3

Chemical Properties

• Melting Point: 68 °C
• Boiling Point: 97 °C
• Flash Point: 204.2°C
• Appearance: /
• Density: 1.22g/cm³
• Vapor Pressure: 1.34E-07mmHg at 25°C
• Refractive Index: 1.624
• PKA: 14.22±0.10(Predicted)
• CAS DataBase Reference: [4-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]METHANOL(160388-56-7)
• EPA Substance Registry System: [4-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]METHANOL(160388-56-7)

Safety Data

• Hazardous Substances Data: 160388-56-7(Hazardous Substances Data)

Usage

General Description

[4-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]METHANOL is a chemical compound with a molecular structure that includes a phenyl group with a triazol-1-ylmethyl substituent. It is also known as 1-(4-Hydroxybenzyl)-1H-1,2,4-triazole and has applications in various industries, including pharmaceuticals and agrochemicals. The compound's unique structure gives it potential bioactive properties and the ability to act as a ligand for metal ions. It can be used as a building block in the synthesis of other organic compounds and as a reagent in chemical reactions. Due to its versatile properties, [4-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]METHANOL is a valuable component in the field of chemical research and development.

InChI:InChI=1/C10H11N3O/c14-6-10-3-1-9(2-4-10)5-13-8-11-7-12-13/h1-4,7-8,14H,5-6H2

Upstream product

• 288-88-0 1,2,4-Triazole 
• 623-25-6 p-Xylylene dichloride 
• 870766-45-3 methyl 4-(1H-1,2,4-triazol-1-ylmethyl)benzoate 
• 26496-94-6 Ethyl 4-(bromomethyl)benzoate 
• 160388-64-7 ethyl 4-(1H-1,2,4-triazol-1-ylmethyl)benzoate 

Downstream Products

• 160388-59-0 4-(1H-1,2,4-triazol-1-ylmethyl)phenylacetonitrile 
• 160388-66-9 4-(1H-1,2,4-triazol-1-ylmethyl)benzyl chloride 

Relevant articles and documents

The ionothermal synthesis of a new 3-D framework based on classic β-[Mo8O26]4? anions

An unusual metal-organic framework, {H[Ag(I)L][Mo(VI)4O13]}n (1) (L=(4-((1H-1,2,4-triazol-1-yl)methyl)phenyl)methanol)), has been obtained under ionothermal conditions. According to the single-crystal X-ray diffraction analysis, 1 is a new 3-D framework based on β-[Mo8O26]4? type polymolybdate anions with two kinds of channels (A and B) along the b-axes and c-axes in the framework. The neighboring inorganic Mo8-Ag chains are linked by the organic ligands through the Ag centers resulting in 2-D layers. These adjacent 2-D layers extend into a 3-D framework through Ag1 nodes and β-[Mo8O26]4? anions, respectively, resulting in a topological symbol (64 · 82)2(64 · 82). In addition, the gas adsorption, proton conduction and luminescent properties of 1 are also discussed in detail. Moreover, the electrochemical impedance spectroscopy (EIS) measurements show a conductivity (1.9 × 10?4 S cm?1 at 65 °C and 95% relative humidity (RH)), with an activation energy of 0.41 eV for 1. The mechanism of proton conduction for 1 is proved to be the vehicular mechanism.

Non-steroidal antiinflammatory agents. Synthesis and enzyme inhibition of 2-[4-(heteroarylmethyl)phenyl]propanoic acids and analogues

Some 2-[4-(heteroarylmethyl)phenyl]propanoic acids and phenylacetic and benzoic analogues have been synthesized. All above acids were tested for their inhibitory activity on lipoxygenase and cyclooxygenase, in comparison with NDGA and tolmetin. 2-[4-(Thie