160388-56-7

Usage

Uses

Used in Pharmaceutical Industry:
[4-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]METHANOL is used as a pharmaceutical intermediate for its potential bioactive properties. Its unique structure allows it to be incorporated into the development of new drugs, particularly in the synthesis of compounds with therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, [4-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]METHANOL is utilized as a precursor in the synthesis of agrochemicals. Its ability to act as a ligand for metal ions makes it a valuable component in the development of compounds with pesticidal or herbicidal properties.
Used in Chemical Research and Development:
[4-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]METHANOL is employed as a building block in the synthesis of other organic compounds. Its versatile properties make it an essential component in the development of new chemical entities with potential applications in various industries.
Used as a Reagent in Chemical Reactions:
Due to its unique structure, [4-(1H-1,2,4-TRIAZOL-1-YLMETHYL)PHENYL]METHANOL serves as a reagent in various chemical reactions. It aids in the formation of new compounds and contributes to the advancement of chemical processes in research and industrial applications.

InChI:InChI=1/C10H11N3O/c14-6-10-3-1-9(2-4-10)5-13-8-11-7-12-13/h1-4,7-8,14H,5-6H2

Upstream product

• 160388-64-7 ethyl 4-(1H-1,2,4-triazol-1-ylmethyl)benzoate 
• 870766-45-3 methyl 4-(1H-1,2,4-triazol-1-ylmethyl)benzoate 
• 288-88-0 1,2,4-Triazole 
• 623-25-6 p-Xylylene dichloride 
• 26496-94-6 Ethyl 4-(bromomethyl)benzoate 

Downstream Products

• 160388-59-0 4-(1H-1,2,4-triazol-1-ylmethyl)phenylacetonitrile 
• 160388-66-9 4-(1H-1,2,4-triazol-1-ylmethyl)benzyl chloride 

Relevant academic research and scientific papers

The ionothermal synthesis of a new 3-D framework based on classic β-[Mo8O26]4? anions

An unusual metal-organic framework, {H[Ag(I)L][Mo(VI)4O13]}n (1) (L=(4-((1H-1,2,4-triazol-1-yl)methyl)phenyl)methanol)), has been obtained under ionothermal conditions. According to the single-crystal X-ray diffraction analysis, 1 is a new 3-D framework based on β-[Mo8O26]4? type polymolybdate anions with two kinds of channels (A and B) along the b-axes and c-axes in the framework. The neighboring inorganic Mo8-Ag chains are linked by the organic ligands through the Ag centers resulting in 2-D layers. These adjacent 2-D layers extend into a 3-D framework through Ag1 nodes and β-[Mo8O26]4? anions, respectively, resulting in a topological symbol (64 · 82)2(64 · 82). In addition, the gas adsorption, proton conduction and luminescent properties of 1 are also discussed in detail. Moreover, the electrochemical impedance spectroscopy (EIS) measurements show a conductivity (1.9 × 10?4 S cm?1 at 65 °C and 95% relative humidity (RH)), with an activation energy of 0.41 eV for 1. The mechanism of proton conduction for 1 is proved to be the vehicular mechanism.

1,2,4-TRIAZOL-l-YL BISPHENYL DERIVATIVES FOR USE IN THE TREATMENT OF ENDOCRINE-DEPENDENT TUMOURS

There is provided a compound of Formula I wherein R3, R4, R5, R6 and R7 are independently selected from H and -Y-R6; wherein each R8 is independently selected from -OH, hydrocarbyl groups, oxyhydrocarbyl groups, cyano (-CN), nitro (-NO2), H-bond acceptors, and halogens; wherein at Jeast one of R3, R4, R5, R6 and R7 is -Y-R8 wherein R8 is selected from substituted and unsubstituted ? heterocyclic rings and amino substituted phenyl groups, wherein X is a bond or a linker group; wherein Y is an optional linker group; and wherein ring A is optionally further , substituted; wherein R9 is selected from H, -OH and -OSO2NR1R2; wherein R1 and R2 are independently selected from H and hydrocarbyl; wherein (a) X is a bond and at least one of R3, R4, R5, R6 and R7 is -Y-R8; OR (b) R9 is -OSO2NR1R2 or - OH and four of R3, R4, R5, R6 and R7 are H and one of R3, R4, R5, R6 and R7 is -Y-R8. These compounds inhibit steroid sulphatase and aronatase activity and are useful in the treatment of endocrine-dependent tumours.

Non-steroidal antiinflammatory agents. Synthesis and enzyme inhibition of 2-[4-(heteroarylmethyl)phenyl]propanoic acids and analogues

Some 2-[4-(heteroarylmethyl)phenyl]propanoic acids and phenylacetic and benzoic analogues have been synthesized. All above acids were tested for their inhibitory activity on lipoxygenase and cyclooxygenase, in comparison with NDGA and tolmetin. 2-[4-(Thie