160453-41-8Relevant articles and documents
Cancer Chemopreventive 3-Substituted-4-oxoretinoic Acids
Shealy, Y. Fulmer,Hosmer, Carla A.,Riordan, James M.,Wille, John W.,Rogers, Tina S.,Hill, Donald L.
, p. 3051 - 3056 (1994)
The introduction of substituents at position 3 of methyl 4-oxoretinoate can be effected in good yields by alkylating the lithium dienolate.A second substituent can be introduced also, but the resulting 3,3-disubstituted-4-oxoretinoates were isolated in lo