160459-99-4Relevant academic research and scientific papers
Synthesis of Isoquinoline Derivatives via Palladium-Catalyzed C?H/C?N Bond Activation of N-Acyl Hydrazones with α-Substituted Vinyl Azides
Jiang, Huanfeng,Nie, Biao,Ren, Qingyun,Wu, Wanqing,Zeng, Wei,Zhang, Ji,Zhang, Yingjun
supporting information, (2020/02/25)
A palladium-catalyzed cyclization of N-acetyl hydrazones with vinyl azides has been developed. Various substituted isoquinolines, including diverse fused isoquinolines can be prepared via this protocol in moderate to good yields. Mechanistic studies suggest that α-substituted vinyl azide serves as an internal nitrogen source. Also, C?H bond activation and C?N bond cleavage have been realized using hydrazone as directing group. (Figure presented.).
Palladium-Catalyzed Carbonylative Synthesis of 3-Methyleneisoindolin-1-ones from Ketimines with Hexacarbonylmolybdenum(0) as the Carbon Monoxide Source
Wang, Zechao,Zhu, Fengxiang,Li, Yahui,Wu, Xiao-Feng
, p. 94 - 98 (2017/01/17)
An interesting procedure for the palladium-catalyzed carbonylative synthesis of 3-methyleneisoindolin-1-ones from ketimines was established. By using Mo(CO)6 (0.3 equiv.) as the solid CO source and through C(sp2)?H bond activation, t
Pyridylacetic acid derivatives, process and intermediate products for their preparation and their use
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, (2008/06/13)
PCT No. PCT/EP96/04576 Sec. 371 Date Apr. 23, 1998 Sec. 102(e) Date Apr. 23, 1998 PCT Filed Oct. 22, 1996 PCT Pub. No. WO97/16427 PCT Pub. Date May 9, 1997Pyridylacetic acids of the formula I wherein X is NOCH3, CHOCH3 and CHCH3; Y is oxygen or NRa; R is
Anticonvulsant properties of various acetylhydrazones, oxamoylhydrazones and semicarbazones derived from aromatic and unsaturated carbonyl compounds
Dimmock, Jonathan R.,Vashishtha, Sarvesh C.,Stables, James P.
, p. 241 - 248 (2007/10/03)
Various acetylhydrazones, oxamoylhydrazones and semicarbazones were prepared as candidate anticonvulsants with a view to examining the viability of a putative binding site hypothesis. Atomic charge calculations were undertaken to determine the hydrogen bo
