160460-40-2

Upstream product

• 6298-96-0 (S)-1-(4-methoxyphenyl)ethylamine 
• 100-52-7 benzaldehyde 

Downstream Products

• 827308-21-4 (S)-[(S)-1-(4-Methoxy-phenyl)-ethylamino]-phenyl-acetonitrile 
• 48108-77-6 (S)-α-phenylglycinenitrile 
• 15028-39-4 L-2-phenylglycine methyl ester hydrochloride 
• 160549-61-1 C₂₀H₂₁NO₄ 
• 160460-39-9 C₂₀H₂₁NO₄ 
• 1164210-80-3 (2R,3R)-1-[(1S)-1-(4-methoxyphenyl)ethyl]-2-phenyl-3-hydroxyazetidine 
• 309757-67-3 tert-butyl (3R,αS)-3-(3-fluorophenyl)-3-(N-benzyl-N-α-methyl-4-methoxybenzylamino)propanoate 
• 309757-69-5 tert-butyl (3R,αS)-3-(3-fluorophenyl)-3-(N-α-methyl-4-methoxybenzylamino)propanoate 
• 445018-43-9 tert-butyl (3R,αS)-3-(N-benzyl-N-α-methyl-4-methoxybenzylamino)pent-4-enoate 
• 445018-44-0 tert-butyl (3R,αS)-3-(N-α-methyl-4-methoxybenzylamino)pent-4-enoate 
• 445018-41-7 (3R,αS)-3-(N-α-methyl-4-methoxybenzylamino)-3-phenylpropionic acid 
• 445018-42-8 (4R,αS)-N-(α-methyl-4-methoxybenzy)-4-phenylazetidin-2-one 
• 445018-45-1 (3R,αS)-3-(N-α-methyl-4-methoxybenzylamino)pent-4-enoic acid 
• 67321-63-5 (R)-N-benzyl-β³-homophenylglycine 

Relevant academic research and scientific papers

Orthogonal N,N-deprotection strategies of β-amino esters

β-Amino esters derived from the stereoselective conjugate addition of homochiral lithium N-benzyl-N-α-methyl-4-methoxybenzylamide to α,β-unsaturated esters may be orthogonally mono-N-deprotected under either oxidative or acid-promoted reaction conditions. Further oxidative deprotection affordsβ-amino acids or β-lactams.

Synthesis, structure, and catalytic activity of a new zinc complex derived from a chiral hydroxyazetidine ligand

A new chiral tetrameric zinc complex [(1)ZnEt]4 (2) has been readily prepared via alkane elimination between ZnEt2 and a chiral azetidine derivative, (2R,3R)-1-[(1S)-1-(4-methoxyphenyl)ethyl]-2-phenyl-3- hydroxyazetidine (1H). Complex 2 has been characterized by various spectroscopic techniques, elemental analyses, and X-ray diffraction analysis. Complex 2 has a cubane-like Zn4O4 core structure, and is an active catalyst for the polymerization of rac-lactide, leading to the heterotactic-rich polylactides.

The asymmetric synthesis of β-haloaryl-β-amino acid derivatives

Lithium N-benzyl-N-α-methyl-4-methoxybenzylamide is employed as a homochiral ammonia equivalent for the asymmetric synthesis of β-haloaryl-β-amino acid derivatives using a conjugate addition/oxidative deprotection strategy.