1604812-73-8

Basic information

• Product Name: C₁₈H₁₂BrF₂N₅O
• Synonyms: C₁₈H₁₂BrF₂N₅O
• CAS NO: 1604812-73-8
• Molecular Weight: 432.227
• Mol File: 1604812-73-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₁₂BrF₂N₅O(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₁₂BrF₂N₅O(1604812-73-8)
• EPA Substance Registry System: C₁₈H₁₂BrF₂N₅O(1604812-73-8)

Safety Data

• Hazardous Substances Data: 1604812-73-8(Hazardous Substances Data)

Upstream product

• 105931-73-5 1-bromo-3-fluoro-4-iodobenzene 
• 918321-20-7 methyl 5-amino-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate 
• 1415559-93-1 methyl 5-[(4-bromo-2-fluorophenyl)amino]-4-fluoro-1-methyl-1H-benzo[d]imidazole-6-carboxylate 
• 288-32-4 1H-imidazole 
• 1604812-72-7 C₁₅H₉BrF₂N₃O₂^(1-)*K⁽¹⁺⁾ 
• 1415564-99-6 6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid 
• 530-62-1 1,1'-carbonyldiimidazole 

Downstream Products

• 1604812-70-5 6-(4-bromo-2-fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid-(2-tert-butoxyethoxy)amide 
• 606143-89-9 6-(4-bromo-2-fluoro-phenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2-hydroxy-ethoxy)-amide 

Relevant articles and documents

PREPARATION OF AND FORMULATION COMPRISING A MEK INHIBITOR

The present invention relates to processes for preparing 6-(4-bromo-2- fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2- hydroxyethyoxy)-amide, processes for preparing crystallized 6-(4-bromo-2- fluorophenylamino)-7-fluoro-3-methyl-3H-benzoimidazole-5-carboxylic acid (2- hydroxyethyoxy)-amide, and intermediates useful therefore. Also provided herein are pharmaceutical compositions comprising this crystallized compound.