1604819-26-2

Upstream product

• 91004-87-4 1-[(ethanesulfonyl)methyl]-3-nitrobenzene 
• 619-23-8 3-Nitrobenzyl chloride 
• 90972-19-3 1-[(ethylsulfanyl)methyl]-3-nitrobenzene 
• 144025-03-6 2,4-difluorophenylboronic acid 
• 1402545-53-2 2-chloro-4-(2,4-difluorophenyl)-5-fluoropyrimidine 

Relevant academic research and scientific papers

4-(ORTHO)-FLUOROPHENYL-5-FLUOROPYRIMIDIN-2-YL AMINES CONTAINING A SULFONE GROUP

The present invention relates to 4-(ortho)-fluorophenyl-5-fluoropyrimidin-2-yl amine derivatives of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).