1402545-53-2

Upstream product

• 2927-71-1 2,4-dichloro-5-fluoropyrimidine 
• 144025-03-6 2,4-difluorophenylboronic acid 

Downstream Products

• 1604819-39-7 4-(2,4-difluorophenyl)-5-fluoro-N-{3-[(methylsulfanyl)methyl]-5-(pentafluoro-λ⁶-sulfanyl)phenyl}pyrimidin-2-amine 
• 1604819-36-4 4-(2,4-difluorophenyl)-5-fluoro-N-{3-[(methylsulfanyl)methyl]-5-(trifluoromethyl)phenyl}pyrimidin-2-amine 
• 1604819-22-8 4-(2,4-difluorophenyl)-5-fluoro-N-{3-[(propan-2-ylsulfonyl)methyl]phenyl}pyrimidin-2-amine 
• 1604819-37-5 [3-{[4-(2,4-difluorophenyl)-5-fluoropyrimidin-2-yl]amino}-5-(pentafluoro-λ⁶-sulfanyl)phenyl]methanol 
• 1604819-26-2 4-(2,4-difluorophenyl)-N-{3-[(ethylsulfonyl)methyl]phenyl}-5-fluoropyrimidin-2-amine 
• 1604819-27-3 4-(2,4-difluorophenyl)-5-fluoro-N-{3-[(propylsulfonyl)methyl]phenyl}pyrimidin-2-amine 
• 1604819-28-4 N-{3-[(cyclopropylsulfonyl)methyl]phenyl}-4-(2,4-difluorophenyl)-5-fluoropyrimidin-2-amine 
• 1610546-26-3 4-(2,4-difluorophenyl)-5-fluoro-N-{3-[((2-methoxyethyl)sulfanyl)methyl]-5-(trifluoromethyl)phenyl}pyrimidin-2-amine 
• 1610545-93-1 (rac)-{[3-{[4-(2,4-difluorophenyl)-5-fluoropyrimidin-2-yl]amino}-5-(trifluoromethyl)benzyl](2-methoxyethyl)oxido-λ⁶-sulfanylidene}cyanamide 
• 1610546-27-4 (rac)-{[3-{[4-(2,4-difluorophenyl)-5-fluoropyrimidin-2-yl]amino}-5-(trifluoromethyl)benzyl](2-methoxyethyl)-λ⁴-sulfanylidene}cyanamide 
• 1610545-79-3 4-(2,4-difluorophenyl)-5-fluoro-N-{3-fluoro-5-[(S-methylsulfonimidoyl)methyl]phenyl}pyrimidin-2-amine 
• 1610545-80-6 4-(2,4-difluorophenyl)-5-fluoro-N-{3-fluoro-5-[(S-methylsulfonimidoyl)methyl]phenyl}pyrimidin-2-amine 
• 1610545-77-1 (rac)-4-(2,4-difluorophenyl)-5-fluoro-N-{3-fluoro-5-[(S-methylsulfonimidoyl)methyl]phenyl}pyrimidin-2-amine 
• 1610545-75-9 (rac)-[(3-{[4-(2,4-difluorophenyl)-5-fluoropyrimidin-2-yl]amino}-5-fluorobenzyl)(methyl)oxido-λ⁶-sulfanylidene]cyanamide 

Relevant academic research and scientific papers

DISUBSTITUTED 5-FLUORO PYRIMIDINE DERIVATIVES CONTAINING A SULFONDIIMINE GROUP

The present invention relates to 5-fluoro pyrimidine derivatives containing a sulfondiimine group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in pa

4-(ORTHO)-FLUOROPHENYL-5-FLUOROPYRIMIDIN-2-YL AMINES CONTAINING A SULFONE GROUP

The present invention relates to 4-(ortho)-fluorophenyl-5-fluoropyrimidin-2-yl amine derivatives of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferative disorders and/or virally induced infectious diseases and/or of cardiovascular diseases. The invention further relates to intermediate compounds useful in the preparation of said compounds of general formula (I).

4-(ORTHO)-FLUOROPHENYL-5-FLUOROPYRIMIDIN-2-YL AMINES CONTAINING A SULFOXIMINE GROUP

The present invention relates to 4-(ortho)-fluorophenyl-5-fluoropyrimidin-2-yl amine derivatives containing a sulfoximine group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or p

DISUBSTITUTED 5-FLUORO-PYRIMIDINES

The present invention relates to disubstituted 5-fluoro-pyrimidines of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of disorders, in particular of hyper-proliferativ

DISUBSTITUTED 5-FLUORO PYRIMIDINE DERIVATIVES CONTAINING A SULFOXIMINE GROUP

The present invention relates to disubstituted 5-fluoro pyrimidine derivatives containing a sulfoximine group of general formula (I) as described and defined herein, and methods for their preparation, their use for the treatment and/or prophylaxis of diso