1605289-20-0Relevant articles and documents
Design, synthesis and evaluation of novel diaryl pyrrolopyrimidine and pyrrolothiazine derivatives as inhibitors of tumor necrosis factor stimulated gene-14 (TSG-14) production
Hilmy, Khalid M.H.,Soliman, Dalia H.,Shahin, Esmat B.A.,El-Deeb, Hala S.,El-Kousy, Salah M.
, p. 419 - 424 (2014/04/17)
A novel series of pyrrolothiazines 2-4 and pyrrolopyrimidines 5-7 have been synthesized. The structures of these compounds were established by spectroscopic and element microanalytical data. The newly synthesized compounds were evaluated as inhibitors of TSG-14. The most effective results were obtained by the S-sec-butyl derivatives 6e (80%) and the N-ethyl derivatives 4e (70%).