1605332-29-3Relevant academic research and scientific papers
Synthesis and structural characterization of pyrrole heterocyclic systems bearing amino acid units: Novel pyrrol-3-ones, pyrrolo[1,2-a][3,1]benzoxazines, and pyrrolo[2,1-b][1,3]oxazoles
Koca, Irfan,Sacmaci, Mustafa,Yilmaz, Filiz,Uengoerena, Sevket Hakan
, p. 212 - 218 (2014/02/14)
Furan-3-one derivatives 1 were converted into 2-hydroxy-pyrrole-3-ones 4 by reacting with various α- and β-amino acids. In contrast, the reaction of furan-3-ones and 1-aminocyclobutanecarboxylic acid afforded spiro-pyrrolo[2,1-b][1,3]oxazoles 5 via the pyrrole-3-one intermediate under the same reaction conditions. Some of 2-hydroxy-pyrrole-3-ones 3 derived from anthranilic acids were transformed to pyrrolo[1,2-a][3,1]benzoxazines via intramolecular esterification.
