160538-64-7

Upstream product

• 100-59-4 phenylmagnesium chloride 
• 148766-15-8 (R,E)-3-but-2-enoyl-4-phenyloxazolidin-2-one 
• 917-54-4 methyllithium 
• 155835-37-3 (4R)-3-(3-phenyl-2-(E)-propenoyl)-4-phenyl-2-oxazolidinone 
• 4593-90-2 3-phenylbutyric acid 
• 102-92-1 Cinnamoyl chloride 
• 90319-52-1 (4R)-phenyl-2-oxazolidinone 
• 591-51-5 phenyllithium 

Downstream Products

• 160636-92-0 (R)-3-((2S,3R)-2-Azido-3-phenyl-butyryl)-4-phenyl-oxazolidin-2-one 
• 128677-94-1 (2S,3R)-2-azido-3-phenylbutanoic acid 
• 25488-27-1 threo-L-(2S,3R)-β-methylphenylalanine 
• 160636-91-9 (R)-3-((2R,3R)-2-Bromo-3-phenyl-butyryl)-4-phenyl-oxazolidin-2-one 

Relevant academic research and scientific papers

Highly diastereoselective conjugate additions of monoorganocopper reagents to chiral imides

Stereoselective conjugate additions to chiral N-enoyl amides employing various monoorganocuprate reagents, Li[RCuI], are described. The presence of TMSI in the addition of Li[RCuI] in THF provided the highest stereoselectivities. Reversed major diastereom

Asymmetric conjugate additions of TMSI promoted monoorganocuprate reagents, Li[RCuI], to various N-enoyl oxazolidinones

Diastereoselective conjugate additions to different α,β-unsaturated N-acyl oxazolidinones using various monoorganocuprate reagents, Li[RCuI], are described. The TMSI activated conjugate addition reactions provided high yields (80-98%) and reversed major d

Exploration for Large-scale Stereoselective Synthesis of Unusual Amino Acids by using 4-Phenyoxazolidin-2-one as a New Chiral Resolution Reagent

Individual isomers of β-branched α-amino acids have been stereoselectively and asymmetrically synthesized in high yield by a new method which uses 4-phenyloxazolidin-2-one as a novel chiral resolution reagent acting simultaneously as the auxiliary.