16055-12-2 Usage
General Description
2,5-dihydrophenylalanine, also known as DOPA, is a chemical compound that is a precursor to dopamine, a neurotransmitter that plays a role in mood regulation, movement, and a variety of other neurological functions. DOPA is a non-essential amino acid, meaning that it can be synthesized within the body. It is also a catecholamine, meaning that it contains a catechol ring structure. DOPA is commonly used in the treatment of Parkinson's disease, as it can help to increase dopamine levels in the brain by crossing the blood-brain barrier and being converted into dopamine by the enzyme DOPA decarboxylase. Additionally, DOPA has been studied for its potential therapeutic effects in other conditions, such as depression and attention deficit hyperactivity disorder (ADHD).
Check Digit Verification of cas no
The CAS Registry Mumber 16055-12-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,6,0,5 and 5 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 16055-12:
(7*1)+(6*6)+(5*0)+(4*5)+(3*5)+(2*1)+(1*2)=82
82 % 10 = 2
So 16055-12-2 is a valid CAS Registry Number.
InChI:InChI=1/C9H13NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-2,5,8H,3-4,6,10H2,(H,11,12)/t8-/m0/s1
16055-12-2Relevant articles and documents
Ozonolysis of (cyclohexa-1,4-dienyl)-L-alanine. An approach to the synthesis of new unnatural aminoacids. X-Ray molecular structure of 2-hydroxy-7-methyl-3-phenylpyrazolopyrimidine
Zvilichovsky, Gury,Gurvich, Vadim
, p. 2509 - 2516 (2007/10/02)
The aromatic ring in L-phenylalanine was transformed into isoxazolyl, N-phenylpyrazolyl, and the bicyclic pyrazolopyrimidinyl groups, by a combination of Birch reduction and ozonolysis, followed by condensation with the relevant binucleophiles.The ozonolysis was carried out on the N-acylated esters of cyclohexa-1,4-dienylalanine.The resulting N-acylated esters of heterocyclic alanine derivatives were obtained without isolation of the ozonolysis products. 4-Phenylpyrazolidine-3,5-dione was used as a 'hydrazine donor' in the construction of pyrazolyl group, as direct condensation with hydrazine was successful.