1606-67-3Relevant articles and documents
Highly selective turn-on probe for H2S with imaging applications in vitro and in vivo
Thirumalaivasan, Natesan,Venkatesan, Parthiban,Wu, Shu-Pao
, p. 13510 - 13515 (2017)
Hydrogen sulfide (H2S) is the third endogenous gaseous signaling molecule, and its distribution affects several biological processes. To clarify the roles of H2S in living systems, the exact determination of H2S in living cells in vivo has become an important issue. Herein, we report a novel pyrene-based fluorescent probe, PyN3, as a H2S turn-on sensor via reduction of azide to amine, which subsequently undergoes self-immolation through intramolecular 1,6-elimination of the p-aminobenzyl moiety, releasing 1-aminopyrene and leading to the recovery of fluorescence intensity. With its high sensitivity, good selectivity, and low cytotoxicity, PyN3 was able to recognize both exogenous and endogenously produced H2S in biological systems. In contrast to the traditional azide-based H2S probes, PyN3 shows efficient and effective selectivity to H2S at biological pH ranges. Because of these promising properties, PyN3 is an excellent probe for visualizing endogenous H2S in vitro and in vivo.
A new processable and fluorescent polydithienylpyrrole electrochrome with pyrene appendages
Tirke?, Seha,Mersini, Jetmire,?zta?, Zahide,Algi, Melek Pamuk,Algi, Fatih,Cihaner, Atilla
, p. 295 - 301 (2013)
A new hybrid compound, namely 1-(pyren-3-yl)-2,5-di(thiophen-2-yl)-1H- pyrrole (SNS-P), was polymerized via both chemical and electrochemical methods. Chemically obtained soluble polydithienylpyrrole (c-PSNS-P) bearing pyrene appendages is a homogeneous and uniform polymer with a number averaged molecular weight of 15,200 g/mol. The polymer exhibits both multi-electrochromic and fluorescent properties. Upon oxidation, the color of electrochemically obtained polymer (e-PSNS-P) changes from yellowish orange to greenish yellow and to green/blue and finally to blue. In addition, the polymer induces yellowish orange (564 nm) and bright orange emission (613 nm) in solution and solid states, respectively.
1,3-Bis(pyren-1-yliminomethyl)calix[4]arene as a selective fluorescent turn-on sensor for mercury(II) ion
Tanaka, Shinya,Hirasawa, Kengo,Watanabe, Kyohei,Hattori, Tetsutaro
, p. 179 - 183 (2018)
A novel calixarene-based diimine, 1,3-bis(pyren-1-yliminomethyl)calix[4]arene (5), serves as a turn-on-type fluorescent sensor, which selectively detects Hg2+ in THF/H2O (99:1, v/v) in the presence of various other metal ions. Such selectivity is not seen with half salen 1 derived from salicylaldehyde and 1-aminopyrene. 1H NMR analysis reveals that it is a chemodosimetric sensor based on its hydrolysis mediated by Hg2+ to release 1-aminopyrene molecules as fluorescent chromophores.
A new pyrene-based Schiff-base: A selective colorimetric and fluorescent chemosensor for detection of Cu(II) and Fe(III)
Bhorge, Yeshwant Ramchandra,Tsai, Haw-Tyng,Huang, Keh-Feng,Pape, Albert J.,Janaki, Sudhakar Narasimha,Yen, Yao-Pin
, p. 7 - 12 (2014)
A new receptor 1 was prepared, for the detection of Cu2+ and Fe3+ in solutions as a colorimetric and fluorescent sensor, respectively. Receptor 1 shows highly selective and sensitive recognition toward Cu2+ and Fe3+ by naked eye UV-Vis and fluorescent color changes in aqueous solution (DMSO/H2O = 8/2, v/v), respectively. The sensitivity toward Cu2+ or Fe3+ was not interfered with by the presence of other metal ions such as Mg2+, Cd2+, Ag+, Zn2+, Ni2+, Co2+, Mn 2+, Cr3+, Ca2+, Na+, Pb 2+, K+, Fe2+, Li+ and Hg 2+ ions. Receptor 1 can be used for semi-quantitative recognition of Cu2+ ions at ppm level. The fluorescence microscopy experiments showed that the receptor is efficient for detection of Fe3+ in vitro, developing a good image of the biological organelles.
Uncovering the true mechanism of optical detection of HSO4 - in water by Schiff-base receptors - Hydrolysis vs. hydrogen bonding
Kumar, Virendra,Kumar, Ajit,Diwan, Uzra,Upadhyay
, p. 9540 - 9542 (2012)
The mechanism of optical detection of HSO4- in aqueous medium by Schiff-base receptors has previously been proposed to depend on selective hydrogen-bond interactions. Here, we clearly demonstrate for the first time that the acidic na
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Goldschmiedt
, p. 580 (1881)
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Tuning of n- and p-type reduced graphene oxide transistors with the same molecular backbone
Lee, Junghyun,Hwang, Eunhee,Lee, Eunkyo,Seo, Sohyeon,Lee, Hyoyoung
, p. 5155 - 5159 (2012)
Play the field: A field-effect transistor using reduced graphene oxides was prepared through the reduction of graphene oxides connected between two electrodes. The use of pyrene with an electron-withdrawing group and an electron-donating group showed the p- and n-doping effects, respectively, while the pyrene backbone with no electron-withdrawing or -donating groups showed no doping effect.
Cobalt-Catalyzed Direct Carbonylative Synthesis of Free (NH)-Benzo[ cd]indol-2(1 H)-ones from Naphthylamides
Ying, Jun,Fu, Lu-Yang,Zhong, Guoqiang,Wu, Xiao-Feng
, p. 5694 - 5698 (2019/07/08)
A cobalt-catalyzed C-H carbonylation of naphthylamides for the synthesis of benzo[cd]indol-2(1H)-one scaffolds has been developed. The reaction employs a traceless directing group and uses benzene-1,3,5-triyl triormate as the CO source, affording various free (NH)-benzo[cd]indol-2(1H)-ones in moderate to high yields (up to 88%). Using this protocol, the total synthesis of BET bromodomain inhibitors A and B was accomplished as well.
