160601-84-3Relevant academic research and scientific papers
Identification and Optimization of the First Highly Selective GLUT1 Inhibitor BAY-876
Siebeneicher, Holger,Cleve, Arwed,Rehwinkel, Hartmut,Neuhaus, Roland,Heisler, Iring,Müller, Thomas,Bauser, Marcus,Buchmann, Bernd
, p. 2261 - 2271 (2016)
Despite the long-known fact that the facilitative glucose transporter GLUT1 is one of the key players safeguarding the increase in glucose consumption of many tumor entities even under conditions of normal oxygen supply (known as the Warburg effect), only
Method for preparing 2-acylamino isonicotinic acid from 2-methyl cyanoisonicotinate
-
Paragraph 0027-0098, (2020/05/01)
The invention discloses a method for preparing 2-acylamino isonicotinic acid from 2-methyl cyanoisonicotinate, wherein the method comprises the steps: adding dioxane, and carrying out a reaction in asodium hydroxide aqueous solution, so as to obviously enhance the yield of 2-acylamino isonicotinic acid. The whole preparation method is simple and easy to operate and is quite suitable for industrial large-scale production.
DOPAMINE D3 RECEPTOR ANTAGONISTS COMPOUNDS
-
Page/Page column 123, (2016/05/19)
The disclosure is directed to novel dopamine D3 receptor antagonists, processes for their preparation, intermediates used in these processes, pharmaceutical compositions containing them and their use in therapy, including treating drug dependency and psychosis.
Process for the preparation of 2,4-pyridine dicarboxylic acid
-
, (2008/06/13)
A process for the preparation of carboxamides of nitrogen-containing aromatic heterocyclic compounds from the corresponding N-heterocyclic compounds by reaction thereof with formamide in the presence of peroxodisulfuric acid or a peroxodisulfate.
