1606171-95-2Relevant academic research and scientific papers
The construction of polysubstituted aromatic core derivatives via a cycloaddition/oxidative aromatization sequence from quinone and β-enamino esters
Li, Yu-Jin,Huang, Huan-Ming,Ye, Qing,Hou, Li-Fen,Yu, Wu-Bin,Jia, Jian-Hong,Gao, Jian-Rong
, p. 421 - 427 (2014)
An unexpected strategy has been discovered for the construction of polysubstituted aromatic core derivatives from the reaction of quinones or N-substituted maleimides with b-enamino esters by a cycloaddition/oxidative aromatization sequence that provides products contrary to those delivered by the Nenitzescu reaction. The current method provides a highly favorable synthetic strategy for the efficient construction of important therapeutic agents containing polysubstituted aromatic core structures.
