160647-67-6

Basic information

• Product Name: (3-nitrophenyl)(pyrrolidin-1-yl)methanone
• Synonyms: (3-nitrophenyl)(pyrrolidin-1-yl)methanone;1-(3-nitrobenzoyl)pyrrolidine
• CAS NO: 160647-67-6
• Molecular Formula: C₁₁H₁₂N₂O₃
• Molecular Weight: 220.22458
• Mol File: 160647-67-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (3-nitrophenyl)(pyrrolidin-1-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (3-nitrophenyl)(pyrrolidin-1-yl)methanone(160647-67-6)
• EPA Substance Registry System: (3-nitrophenyl)(pyrrolidin-1-yl)methanone(160647-67-6)

Safety Data

• Hazardous Substances Data: 160647-67-6(Hazardous Substances Data)

Usage

Description

(3-nitrophenyl)(pyrrolidin-1-yl)methanone is a chemical compound with the molecular formula C11H12N2O3. It is composed of a nitrophenyl group, a pyrrolidin-1-yl group, and a methanone group. (3-nitrophenyl)(pyrrolidin-1-yl)methanone is commonly known as an intermediate in the synthesis of pharmaceuticals and agrochemicals, and it may also be used in research and development. The nitrophenyl group is a nitro-substituted aromatic ring that can be reactive and is often used in organic synthesis as an electrophile. The pyrrolidin-1-yl group is a five-membered heterocyclic ring that is commonly found in pharmaceutical compounds and has various biological activities. The methanone group is a functional group containing a carbonyl group bonded to a hydrogen atom. Due to its unique chemical properties and reactivity, (3-nitrophenyl)(pyrrolidin-1-yl)methanone has potential applications in the pharmaceutical and agricultural industries.

Uses

Used in Pharmaceutical Industry:
(3-nitrophenyl)(pyrrolidin-1-yl)methanone is used as an intermediate in the synthesis of pharmaceuticals for its reactivity and unique chemical properties. It can be used to develop new drugs with various biological activities.
Used in Agrochemical Industry:
(3-nitrophenyl)(pyrrolidin-1-yl)methanone is used as an intermediate in the synthesis of agrochemicals for its potential applications in developing new pesticides or other agricultural chemicals.
Used in Research and Development:
(3-nitrophenyl)(pyrrolidin-1-yl)methanone is used as a research compound to explore its unique chemical properties and reactivity, which can lead to the development of new applications in various industries.

Upstream product

• 123-75-1 pyrrolidine 
• 121-90-4 m-nitrobenzoic acid chloride 
• 121-92-6 3-nitrobenzoic acid 

Downstream Products

• 160647-74-5 (3-aminophenyl)-(pyrrolidin-1-yl)methanone 
• 1187051-99-5 (2-(3-methylbut-2-enyl)-5-nitrophenyl)(pyrrolidin-1-yl)methanone 

Relevant articles and documents

METHODS OF CONTROLLING CROP PESTS USING AROMATIC AMIDE INSECT REPELLENTS, METHODS OF MAKING AROMATIC AMIDE INSECT REPELLENTS, AND NOVEL AROMATIC AMIDE INSECT REPELLENTS

Methods of protecting fruit crops from flying insect pests and of repelling flying insects using aromatic amide compounds are disclosed. The methods apply the compounds to various surfaces, such as the fruit crops, the ground or structures adjacent to the fruit crops, or an object, article, human skin or animal. The compounds have the formula RxC6Hy—C(═O)—N(Cy), where RxC6Hy is a substituted phenyl group, each R group is independently C1-C6 alkyl, substituted C1-C4 alkyl, (substituted) C6-C10 aryl, C1-C4 alkoxy, C6-C10 aryloxy, halogen, nitro, cyano, cyanate, isocyanate, nitroso, C1-C4 alkylthio, phenylthio, (halogen-substituted) C1-C4 alkylsulfonyl, phenylsulfonyl, tolylsulfonyl, amino, mono- or di-C1-C4 alkylamino, diphenylamino, di-C1-C4 alkylamido, formyl, C2-C7 acyl, or C1-C6 alkoxycarbonyl; x is an integer of 1 to 5; x+y=5; Cy is a C2-C8 (substituted) alkadiyl, a C4-C6 (substituted) alkenediyl, or a (substituted) diyl of the formula —(CH2CH2)—O—(CH2CH2)—, —(CH2CH2)—NR′—(CH2CH2)— or —(CH2CH2)—S—(CH2CH2)— that, along with the amide N atom, forms a non-aromatic cyclic group; and R′ is C1-C6 alkyl, substituted C1-C4 alkyl, (substituted) C6-C10 aryl, or (substituted) benzyl.

Direct allylation of aromatic and α,β-unsaturated carboxamides under ruthenium catalysis

The ruthenium-catalyzed oxidative allylation of aromatic and α,β-unsaturated carboxamides with allylic carbonates is described. These transformations proceed readily with complete linear γ-selectivity of substituted allylic carbonates. the Partner Organisations 2014.

IMIDAZO [1,2-A] PYRIDINES AND THEIR PHARMACEUTICAL USE

The invention relates to novel bradykinin antagonists of the formula: STR1 wherein R 1 is halogen,R 2 and R 3 are each hydrogen, lower alkyl, halo(lower)alkyl or acyl,R 4 is aryl having suitable substituent(s), or a heterocyclic group optionally having suitable substituent(s),Q is O or N--R 11, in which R 11 is hydrogen or acyl, andA is lower alkylene,and pharmaceutically acceptable salts thereof.