1606589-54-1

Basic information

• Product Name: 1-(4-bromophenyl)-4-hydroxy-3-methylenepyrrolidin-2-one
• Synonyms: 1-(4-bromophenyl)-4-hydroxy-3-methylenepyrrolidin-2-one
• CAS NO: 1606589-54-1
• Molecular Weight: 268.11
• Mol File: 1606589-54-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(4-bromophenyl)-4-hydroxy-3-methylenepyrrolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-bromophenyl)-4-hydroxy-3-methylenepyrrolidin-2-one(1606589-54-1)
• EPA Substance Registry System: 1-(4-bromophenyl)-4-hydroxy-3-methylenepyrrolidin-2-one(1606589-54-1)

Safety Data

• Hazardous Substances Data: 1606589-54-1(Hazardous Substances Data)

Upstream product

• 1606589-30-3 C₁₁H₁₂BrNO₂ 
• 1606589-19-8 C₁₇H₂₆BrNO₂Si 
• 1338326-88-7 4-bromo-N-[2-[tert-butyl(dimethyl)silyl]oxyethyl]aniline 
• 55110-99-1 2-(4-bromophenylamino)ethan-1-ol 
• 1606589-42-7 C₁₁H₁₀BrNO₂ 

Relevant articles and documents

The acrylamide moiety as an activated alkene component in the intramolecular Baylis-Hillman reaction: Facile synthesis of functionalized α-methylene lactam and spirolactam frameworks

A facile strategy for the intramolecular Baylis-Hillman reaction by utilizing an acrylamide moiety as an activated alkene component was developed, which thus provides a convenient protocol for obtaining five-and six-membered α-methylene lactam and spirolactam derivatives. An intramolecular Baylis-Hillman reaction by using an acrylamide moiety as an activated alkene and an aldehyde as the electrophile component is described. Thus, a simple synthetic strategy for obtaining α-methylene (γ-and δ-)lactam and spiro-γ-lactam derivatives is provided. DABCO = 1,4-diazabicyclo[2.2. 2]octane. Copyright