1338326-88-7

Basic information

• Product Name: 4-bromo-N-[2-[tert-butyl(dimethyl)silyl]oxyethyl]aniline
• Synonyms: 4-bromo-N-[2-[tert-butyl(dimethyl)silyl]oxyethyl]aniline
• CAS NO: 1338326-88-7
• Molecular Weight: 330.34
• Mol File: 1338326-88-7.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 4-bromo-N-[2-[tert-butyl(dimethyl)silyl]oxyethyl]aniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-N-[2-[tert-butyl(dimethyl)silyl]oxyethyl]aniline(1338326-88-7)
• EPA Substance Registry System: 4-bromo-N-[2-[tert-butyl(dimethyl)silyl]oxyethyl]aniline(1338326-88-7)

Safety Data

• Hazardous Substances Data: 1338326-88-7(Hazardous Substances Data)

Upstream product

• 55110-99-1 2-(4-bromophenylamino)ethan-1-ol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 86864-60-0 2-(tert-butyldimethylsilyloxy)ethyl bromide 
• 106-40-1 4-bromo-aniline 

Downstream Products

• 1606589-19-8 C₁₇H₂₆BrNO₂Si 
• 1606589-30-3 C₁₁H₁₂BrNO₂ 
• 1606589-42-7 C₁₁H₁₀BrNO₂ 
• 1606589-54-1 1-(4-bromophenyl)-4-hydroxy-3-methylenepyrrolidin-2-one 
• 1429119-76-5 C₂₁H₁₈ClN₅O₃ 
• 1338326-37-6 4-amino-6-(2'-fluorobiphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one 
• 1338327-21-1 N-(4-bromophenyl)-N-(2-(tert-butyldimethylsilyloxy)ethyl)-4,6-dichloro-2-methylpyrimidine-5-carboxamide 
• 1338326-83-2 methyl 2-(40-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)-2-chlorobiphenyl-4-yl)acetate 
• 1338327-18-6 4-amino-6-(4-bromophenyl)-2-methyl-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one 
• 1338326-64-9 4-amino-6-(2'-chlorobiphenyl-4-yl)-2-methyl-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one 
• 1338327-09-5 tert-butyl 3-(((4'-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)-2-chlorobiphenyl-4-yl)methyl)(methyl)amino)-3-oxopropylcarbamate 
• 1338326-61-6 3-amino-N-((4'-(4-amino-5-oxo-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-6(5H)-yl)-2-chlorobiphenyl-4-yl)methyl)-N-methylpropanamide 
• 1338327-06-2 (S)-4-amino-6-(4'-((3-(tert-butyldimethylsilyloxy)-2-oxopyrrolidin-1-yl)methyl)-2'-chlorobiphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one 
• 1338326-60-5 (S)-4-amino-6-(2'-chloro-4'-((3-hydroxy-2-oxopyrrolidin-1-yl)methyl)biphenyl-4-yl)-7,8-dihydropyrimido[5,4-f][1,4]oxazepin-5(6H)-one 

Relevant articles and documents

The acrylamide moiety as an activated alkene component in the intramolecular Baylis-Hillman reaction: Facile synthesis of functionalized α-methylene lactam and spirolactam frameworks

A facile strategy for the intramolecular Baylis-Hillman reaction by utilizing an acrylamide moiety as an activated alkene component was developed, which thus provides a convenient protocol for obtaining five-and six-membered α-methylene lactam and spirolactam derivatives. An intramolecular Baylis-Hillman reaction by using an acrylamide moiety as an activated alkene and an aldehyde as the electrophile component is described. Thus, a simple synthetic strategy for obtaining α-methylene (γ-and δ-)lactam and spiro-γ-lactam derivatives is provided. DABCO = 1,4-diazabicyclo[2.2. 2]octane. Copyright

Discovery and optimization of efficacious neutral 4-amino-6-biphenyl-7,8- dihydropyrimido[5,4-f][1,4]oxazepin-5-one diacylglycerol acyl transferase-1 (DGAT1) inhibitors

A series of neutral DGAT1 inhibitors with good potency and pharmacokinetics (PK) has been designed by modification of an acidic startpoint. This was achieved by selecting the acid with the highest ligand lipophilicity efficiency (LLE) and replacing the ac