1606590-41-3Relevant academic research and scientific papers
Divergent syntheses of fused β-naphthol and indene scaffolds by rhodium-catalyzed direct and decarbonylative alkyne-benzocyclobutenone couplings
Chen, Peng-Hao,Xu, Tao,Dong, Guangbin
supporting information, p. 1674 - 1678 (2014/03/21)
A tunable rhodium-catalyzed intramolecular alkyne insertion reaction proceeding through the C-C cleavage of benzocyclobutenones is described. Selective formation of either the direct or decarbonylative insertion product can be controlled by using different catalytic systems. A variety of fused β-naphthol and indene scaffolds were obtained in good yields with high functional group tolerance. This work illustrates a divergent approach to synthesize fused-ring systems by C-C activation/functionalization. Cat. in control: A tunable rhodium-catalyzed intramolecular alkyne insertion reaction proceeding through C-C cleavage of benzocyclobutenones is described. Selective formation of either the direct or decarbonylative insertion product can be controlled by using different catalytic systems. A variety of fused β-naphthol and indene scaffolds were obtained in good yields with high functional-group tolerance. Copyright
