160699-02-5

Basic information

• Product Name: Benzenebutanoyl chloride, 4-Methyl-
• Synonyms: Benzenebutanoyl chloride, 4-Methyl-;4-(4-methylphenyl)butanoyl chloride
• CAS NO: 160699-02-5
• Molecular Formula: C₁₁H₁₃ClO
• Molecular Weight: 196.67332
• Mol File: 160699-02-5.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 282.4±19.0 °C(Predicted)
• Appearance: /
• Density: 1.092±0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzenebutanoyl chloride, 4-Methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenebutanoyl chloride, 4-Methyl-(160699-02-5)
• EPA Substance Registry System: Benzenebutanoyl chloride, 4-Methyl-(160699-02-5)

Safety Data

• Hazardous Substances Data: 160699-02-5(Hazardous Substances Data)

Upstream product

• 4521-22-6 4-(4-methylphenyl)butyric acid 

Downstream Products

• 128100-30-1 5-(4-methylphenyl)pyrrolidin-2-one 
• 1378964-52-3 (4R)-4-methyl-4-(2-{1-methyl-5-[4-(4-methylphenyl)butanoyl]-1H-pyrrol-2-yl}ethyl)-1,3-oxazolidin-2-one 
• 827344-05-8 CS-0777 
• 1111702-06-7 N-(4,4-diethoxybutyl)-4-(4-methylphenyl)-butyramide 
• 863032-04-6 (2R)-1-acetoxy-2-acetylamino-2-methyl-4-{1-ethyl-5-[4-(4-methylphenyl)-1-(4-(4-methylphenyl)butanoyloxy)but-1-enyl]pyrrol-2-yl}butane 
• 827344-06-9 (2R)-1-acetoxy-2-acetylamino-2-methyl-4-{1-methyl-5-[4-(4-methylphenyl)-1-(4-(4-methylphenyl)butanoyloxy)but-1-enyl]pyrrol-2-yl}butane 
• 29304-62-9 6-methyl-4-phenyl-1,2-dihydro-naphthalene 
• 6939-38-4 N-(7-methyl-[1]naphthyl)-acetamide 
• 6939-34-0 7-methyl-[1]naphthylamine 
• 1680-51-9 6-methyl-1,2,3,4-tetrahydronaphthalene 
• 56137-91-8 7-methyl-naphthyl-1-acetic acid 
• 22009-37-6 7-methyl-3,4-dihydro-2H-naphthalen-1-one 
• 18211-37-5 2-hydroxy-3-(3-(4-tolyl)propyl)-1,4-naphthoquinone 

Relevant articles and documents

Enantioselective Remote C(sp3)-H Cyanation via Dual Photoredox and Copper Catalysis

The remote C(sp3)-H cyanation of carboxamides has been described by merging photoredox and copper catalysis in a site-selective and enantiocontrolled manner. The protocol is the integration of photoinduced and nitrogen-centered radical-mediated intermolecular hydrogen atom transfer with chiral copper-complex-catalyzed radical cyanation. This strategy gives enantio-enriched cyanated amides in high yields.

Ruthenium(II)-Catalyzed Enantioselective γ-Lactams Formation by Intramolecular C-H Amidation of 1,4,2-Dioxazol-5-ones

We report the Ru-catalyzed enantioselective annulation of 1,4,2-dioxazol-5-ones to furnish γ-lactams in up to 97% yield and 98% ee via intramolecular carbonylnitrene C - H insertion. By employing chiral diphenylethylene diamine (dpen) as ligands bearing electron-withdrawing arylsulfonyl substituents, the reactions occur with remarkable chemo- and enantioselectivities; the competing Curtius-type rearrangement was largely suppressed. Enantioselective nitrene insertion to allylic/propargylic C - H bonds was also achieved with remarkable tolerance to the C=C and C=C bonds.

INHIBITORS OF RAC1 AND USES THEREOF FOR TREATING CANCERS

The present invention concerns a compound having the following formula (I): wherein: - A is in particular -N(R'a)-C(=O)-R, R'a being H or a (C1-C6)alkyl group, and R being preferably a group having the following formula (II): - X is in particular chosen from the group consisting of: -SO2-N(R'b)-, R'b being H or a (C1-C6)alkyl group, -N(R"b)-SO2-, R"b being H or a (C1-C6)alkyl group, -CO-NH-, and -NH-CO-, for use for the treatment of cancers, such as metastatic cancers.