1607-30-3

Basic information

• Product Name: Peroxide,bis(2-methyl-1-oxobutyl) (9CI)
• Synonyms: Peroxide,bis(2-methylbutyryl) (7CI,8CI); 2-Methylbutanoyl peroxide
• CAS NO: 1607-30-3
• Molecular Formula: C₁₀H₁₈O₄
• Molecular Weight: 202.25
• Mol File: 1607-30-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 360°C (estimate)
• Density: 0.9751 (rough estimate)
• Refractive Index: 1.4530 (estimate)
• CAS DataBase Reference: Peroxide,bis(2-methyl-1-oxobutyl) (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Peroxide,bis(2-methyl-1-oxobutyl) (9CI)(1607-30-3)
• EPA Substance Registry System: Peroxide,bis(2-methyl-1-oxobutyl) (9CI)(1607-30-3)

Safety Data

• Hazard Codes: 3:
• Safety Statements: PEROXIDES, INORGANIC; PEROXIDES, ORGANIC." target="_blank">The pure material is unstable and explodes at room temperature. When
• Hazardous Substances Data: 1607-30-3(Hazardous Substances Data)

Upstream product

• 116-53-0 2-Methylbutanoic acid 
• 5856-79-1 iso-butyl chloroformate 
• 1565-80-6 (2S)-2-methyl-1-butanol 
• 1730-91-2 (S)-2-Methylbutyric acid 
• 27763-54-8 (S)-2-methylbutanoyl chloride 

Downstream Products

• 10307-61-6 ethyl (S)-(+)-2-methylbutanoate 
• 869-08-9 (S)-2-methyl-butyric acid-((S)-sec-butyl ester) 
• 23033-63-8 3-methyl-1-phenyl-1-pentanone 

Relevant articles and documents

Radical alkylation of C(sp3)-H bonds with diacyl peroxides under catalyst-free conditions

Herein, we describe a protocol for alkylation reactions of C(sp3)-H bonds with diacyl peroxides by means of a process involving cross-coupling between an alkyl radical and an α-Aminoalkyl radical. The mild, catalyst-And additive-free conditions make this protocol superior to previously reported C(sp3)-H alkylation strategies. The protocol was applied to 1,2,3,4-Tetrahydroisoquinolines and a tetrahydro-β-carboline derivative and could be carried out on a gram scale, indicating its utility for the alkylation of late-stage synthetic intermediates.

Copper(I)-catalyzed tandem reaction: Synthesis of 1,4-disubstituted 1,2,3-triazoles from alkyl diacyl peroxides, azidotrimethylsilane, and alkynes

A copper-catalyzed azide-alkyne cycloaddition (CuAAC) reaction for the synthesis of 1,4-disubstituted 1,2,3-triazoles from alkyl diacyl peroxides, azidotrimethylsilane, and terminal alkynes is reported. The alkyl carboxylic acids is for the first time being used as the alkyl azide precursors in the form of alkyl diacyl peroxides. This method avoids the necessity to handle organic azides, as they are generated in situ, making this protocol operationally simple. The Cu(I) catalyst not only participates in the alkyl diacyl peroxides decomposition to afford alkyl azides but also catalyzes the subsequent CuAAC reaction to produce the 1,2,3-triazoles.

Spectroscopic evidence for the generation of singlet oxygen dimers

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