23033-63-8

Basic information

• Product Name: 1-Pentanone, 3-methyl-1-phenyl-
• Synonyms: 3-methyl-1-phenyl-pentan-1-one;2-methylbutyl phenyl ketone;3-methyl-1-phenyl-1-pentanone;1-Pentanone,3-methyl-1-phenyl
• CAS NO: 23033-63-8
• Molecular Formula: C12H16O
• Molecular Weight: 176.258
• Mol File: 23033-63-8.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: 1-Pentanone, 3-methyl-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pentanone, 3-methyl-1-phenyl-(23033-63-8)
• EPA Substance Registry System: 1-Pentanone, 3-methyl-1-phenyl-(23033-63-8)

Safety Data

• Hazardous Substances Data: 23033-63-8(Hazardous Substances Data)

Upstream product

• 591-51-5 phenyllithium 
• 513-48-4 2-butyl iodide 
• 777882-10-7 α-1-adamantoxystyrene 
• 29394-58-9 (S)-1-iodo-2-methyl-butane 
• 53178-41-9 2-lithio-2-phenyl-1,3-dithiane 
• 28977-69-7 α(+)-2-Methylvalerylchlorid 
• 71-43-2 benzene 
• 53317-06-9 B-sec-butyl-9-borabicyclo<3.3.1>nonane 
• 70-11-1 α-bromoacetophenone 
• 78386-38-6 1-tert-butoxy-1-phenylethene 
• 105-43-1 (S)-3-methyl-pentanoic acid 
• 534-00-9 (S)-2-methylbutyl bromide 
• 137-32-6 (+/-)-2-methyl-1-butanol 
• 495-41-0 1-phenylbut-2-en-1-one 

Downstream Products

• 26372-59-8 (S)-(+)-3-Methyl-1-phenylpentan 
• 78976-22-4 (S)-(+)-1-(3-Methylpentyl)-4-nitrobenzol 
• 78976-21-3 (S)-(+)-1-(3-Methylpentyl)-2-nitrobenzol 
• 79027-65-9 cis-(S,S)-(+)-4,4'-Bis(3-methylpentyl)azobenzol 
• 79027-66-0 trans-(S,S)-(+)-4,4'-Bis(3-methylpentyl)azobenzol 
• 78976-10-0 cis-(S,S)-(-)-2,2'-Bis(3-methylpentyl)azobenzol 
• 78976-11-1 trans-(S,S)-(-)-2,2'-Bis(3-methylpentyl)azobenzol 

Relevant articles and documents

Fe-Catalyzed decarbonylative alkylation-peroxidation of alkenes with aliphatic aldehydes and hydroperoxide under mild conditions

A convenient Fe-catalyzed decarbonylative alkylation-peroxidation of alkenes with aliphatic aldehydes and TBHP to provide chain elongated peroxides is developed, which is further applied to the one-pot synthesis of alkylated ketones. Aliphatic aldehydes were decarbonylated into 1°, 2° and 3° alkyl radicals at low temperature which subsequently allows the cascade construction of C(sp3)-C(sp3) and C(sp3)-O bonds via radical insertion and radical-radical coupling. Various alkenes including mono-substituted, terminally disubstituted or internally disubstituted styrenes bearing synthetically useful functional groups and electron-poor acrylates were tolerated.

Iron-Catalyzed Oxyalkylation of Terminal Alkynes with Alkyl Iodides

A general oxyalkylation of terminal alkynes enabled by iron catalysis has been developed. Primary and secondary alkyl iodides acted as the alkylating reagents and afforded a range of α-alkylated ketones under mild reaction conditions. Acetyl tert-butyl peroxide (TBPA) was used as the radical relay precursor, providing the initiated methyl radical to start the radical relay process. Preliminary mechanistic studies were conducted, and late-stage functionalizations of natural product derivatives were performed.

Oxidative C-C bond cleavage of aldehydes via visible-light photoredox catalysis

The visible-light mediated oxidative C-C bond cleavage of aldehydes has been achieved in good yields at ambient temperature and open to air using Ru(bpy)3Cl2 (bpy = 2,2′-bipyridine) as the photoredox catalyst. Moreover, we further demonstrated the application in a tandem Michael/oxidative C-C bond cleavage reaction.