1607447-89-1Relevant academic research and scientific papers
A kind of four-ring naphtho oxazole derivative and its preparation method
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Paragraph 0048-0051, (2017/10/22)
The invention discloses a novel tetracyclonaphthooxazole derivative. The structure of the novel tetracyclonaphthooxazole derivative is represented by general formula (I) shown in the specification. The invention also discloses a preparation method of the
Naphthoquinone-directed C-H annulation and Csp3-H bond cleavage: One-pot synthesis of tetracyclic naphthoxazoles
Wang, Meining,Zhang, Chi,Sun, Li-Ping,Ding, Chunyong,Zhang, Ao
, p. 4553 - 4560 (2014/06/09)
One-pot synthesis of tetracyclic naphthoxazole derivatives from electron-deficient naphthoquinones and alkynes was achieved via Rh(III)-catalyzed C-H activation and Csp3-H bond cleavage for the first time. This approach proceeds through a tandem cascade process involving substrate tautomerization, C-H activation, oxidative addition, cyclization, and aromatization. In addition, broad substrate scope, simple starting materials, and steric tolerance make this strategy of great practicality.
