1607461-41-5Relevant academic research and scientific papers
Dual C-H functionalization of N-aryl amines: Synthesis of polycyclic amines via an oxidative povarov approach
Min, Chang,Sanchawala, Abbas,Seidel, Daniel
, p. 2756 - 2759 (2014)
Iminium ions generated in situ via copper(I) bromide catalyzed oxidation of N-aryl amines readily undergo [4 + 2] cycloadditions with a range of dienophiles. This method involves the functionalization of both a C(sp 3)-H and a C(sp2)-H bond and enables the rapid construction of polycyclic amines under relatively mild conditions.
