1607464-65-2Relevant academic research and scientific papers
Synthesis, biological evaluation, hydration site thermodynamics, and chemical reactivity analysis of α-keto substituted peptidomimetics for the inhibition of Plasmodium falciparum
Weldon, David J.,Shah, Falgun,Chittiboyina, Amar G.,Sheri, Anjaneyulu,Chada, Raji Reddy,Gut, Jiri,Rosenthal, Philip J.,Shivakumar, Develeena,Sherman, Woody,Desai, Prashant,Jung, Jae-Chul,Avery, Mitchell A.
, p. 1274 - 1279 (2014/03/21)
A new series of peptidomimetic pseudo-prolyl-homophenylalanylketones were designed, synthesized and evaluated for inhibition of the Plasmodium falciparum cysteine proteases falcipain-2 (FP-2) and falcipain-3 (FP-3). In addition, the parasite killing activ
