16076-27-0

Basic information

• Product Name: 2-Bromo-4,5-dichloro-1H-imidazole
• Synonyms: 2-bromo-4,5-dichloro-imidazol;2-BROMO-4,5-DICHLOROIMIDAZOLE;2-BROMO-4,5-DICHLORO-1H-IMIDAZOLE;BUTTPARK 29\04-87;2-Bromine-4,5-Dichloroimidazole
• CAS NO: 16076-27-0
• Molecular Formula: C₃HBrCl₂N₂
• Molecular Weight: 215.86
• EINECS: -0
• Product Categories: Halogenated Heterocycles;Heterocyclic Building Blocks;Imidazoles;ImidazolesBuilding Blocks
• Mol File: 16076-27-0.mol

Chemical Properties

• Melting Point: 223 °C (dec.)(lit.)
• Boiling Point: 350.788 °C at 760 mmHg
• Flash Point: 165.951 °C
• Appearance: /
• Density: 2.136 g/cm³
• Vapor Pressure: 4.29E-05mmHg at 25°C
• Refractive Index: 1.636
• Storage Temp.: 2-8°C
• PKA: 6.32±0.10(Predicted)
• BRN: 606732
• CAS DataBase Reference: 2-Bromo-4,5-dichloro-1H-imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Bromo-4,5-dichloro-1H-imidazole(16076-27-0)
• EPA Substance Registry System: 2-Bromo-4,5-dichloro-1H-imidazole(16076-27-0)

Safety Data

• Hazard Codes: Xi,Xn
• Statements: 36/37/38-20/21/22
• Safety Statements: 26-36-36/37/39
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• RTECS: NI3517500
• Hazardous Substances Data: 16076-27-0(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
2-Bromo-4,5-dichloro-1H-imidazole is used as a key intermediate in the synthesis of various chemical compounds, particularly those with insecticidal properties. Its unique halogenated structure allows for further functionalization and the creation of new molecules with specific biological activities.
Used in Insecticide Development:
In the agricultural industry, 2-Bromo-4,5-dichloro-1H-imidazole is used as a precursor for the synthesis of 1-methoxymethyl-2-bromo-4,5-dichloroimidazole, which exhibits potent insecticidal activity. 2-Bromo-4,5-dichloro-1H-imidazole serves as an effective tool for controlling pests and protecting crops, contributing to increased agricultural productivity and reduced reliance on harmful chemical pesticides.
Used in Pharmaceutical Research:
2-Bromo-4,5-dichloro-1H-imidazole is also utilized in the pharmaceutical industry for the synthesis of 2-substituted 4,5-dichloroimidazoles. These compounds can be further developed into potential therapeutic agents, thanks to the novel approach that avoids the need for N-protection, which simplifies the synthesis process and allows for the exploration of a wider range of chemical modifications.

InChI:InChI=1/C3HBrCl2N2/c4-3-7-1(5)2(6)8-3/h(H,7,8)

Upstream product

• 15965-30-7 4,5-dichloroimidazole 

Downstream Products

• 64736-53-4 4,5-dichloro-imidazole-2-carboxylic acid 
• 81293-98-3 2',6'-dimethoxyphenyl-4,5-dichloroimidazol-2-ylcarbinol 
• 81294-00-0 2',3'-dimethoxyphenyl-4,5-dichloroimidazol-2-ylcarbinol 
• 104473-89-4 1-ethoxymethyl-2-bromo-4,5-dichloroimidazole 
• 104473-90-7 1-n-propyloxymethyl-2-bromo-4,5-dichloroimidazole 
• 136480-53-0 2-Bromo-4,5-dichloro-1-pentyloxymethyl-1H-imidazole 
• 801303-82-2 2-bromo-4,5-dichloro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)imidazole 
• 40532-98-7 1-benzyl-2-bromo-4,5-dichloro-1H-imidazole 

Relevant articles and documents

FLEXIBLE PIEZOELECTRIC AND FERROELECTRIC HALOIMIDAZOLE CRYSTALS

Provided herein are substituted haloimidazole crystals, the substituted haloimidazole crystal comprising a substituted haloimidazole compound wherein the substituents are selected from the group consisting of hydrogen, an alkyl, and a halogen. The substituted haloimidazole crystals may further comprise second substituted haloimidazole. The substituted haloimidazole crystals may be piezoelectric, ferroelectric, flexible, or any combination thereof. Also provided herein are methods for preparing substituted haloimidazole crystals.