1607788-94-2Relevant academic research and scientific papers
Copper-γ-cyclodextrin complexes immobilized on hexagonal boron nitride as an efficient catalyst in the multicomponent synthesis of 1,2,3-triazoles
Nie, Ruifang,Sang, Rui,Ma, Xiaojun,Zheng, Yang,Cheng, Xu,Li, Weijian,Guo, Li,Jin, Hui,Wu, Yong
, p. 286 - 292 (2016)
A copper-γ-cyclodextrin complex immobilized on hexagonal boron nitride (h-BN@γ-CD@Cu(OAc)2) has been prepared for the first time. This recoverable and reusable heterogeneous catalyst can be used in the click synthesis of 1,2,3-triazoles via a one-pot three-component reaction of boracic acid, terminal alkynes, and sodium azide at room temperature in water. FT-IR, XRD, SEM, XPS, TG, and ICP-AES techniques were used to characterize the catalyst. In general, this reaction, with the aid of this new catalyst, afforded the corresponding products with good yields and excellent tolerance of the functional groups.
Azide–Alkyne Cycloaddition (CuAAC) in Alkane Solvents Catalyzed by Fluorinated NHC Copper(I) Complex
Topchiy, Maxim A.,Ageshina, Alexandra A.,Gribanov, Pavel S.,Masoud, Salekh M.,Akmalov, Timur R.,Nefedov, Sergey E.,Osipov, Sergey N.,Nechaev, Mikhail S.,Asachenko, Andrey F.
supporting information, p. 1016 - 1020 (2018/12/11)
A highly efficient and environmentally benign protocol for copper-catalyzed alkyne–azide cycloaddition (CuAAC) in industrially important alkane solvents was developed. New copper(I) complexes bearing NHC ligands decorated with bulky hexafluoroisopropylalk
Indoles rather than triazoles from the ruthenium porphyrin-catalyzed reaction of alkynes with aryl azides
Zardi, Paolo,Savoldelli, Andrea,Carminati, Daniela Maria,Caselli, Alessandro,Ragaini, Fabio,Gallo, Emma
, p. 3820 - 3823 (2015/01/08)
An unprecedented reactivity of aryl azides toward alkynes is presented herein. The reaction performed well in the presence of 2 mol % of ruthenium porphyrin catalysts and afforded substituted indoles instead of triazoles. The procedure is particularly app
Preliminary investigations into triazole derived androgen receptor antagonists
Altimari, Jarrad M.,Niranjan, Birunthi,Risbridger, Gail P.,Schweiker, Stephanie S.,Lohning, Anna E.,Henderson, Luke C.
, p. 2692 - 2706 (2014/05/06)
A range of 1,4-substituted-1,2,3-N-phenyltriazoles were synthesized and evaluated as non-steroidal androgen receptor (AR) antagonists. The motivation for this study was to replace the N-phenyl amide portion of small molecule antiandrogens with a 1,2,3-tri
