1608477-78-6

Basic information

• Product Name: 8-chloro-3-[(4-fluorophenyl)sulfinyl]quinoline
• Synonyms: 8-chloro-3-[(4-fluorophenyl)sulfinyl]quinoline
• CAS NO: 1608477-78-6
• Molecular Weight: 305.76
• Mol File: 1608477-78-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 8-chloro-3-[(4-fluorophenyl)sulfinyl]quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 8-chloro-3-[(4-fluorophenyl)sulfinyl]quinoline(1608477-78-6)
• EPA Substance Registry System: 8-chloro-3-[(4-fluorophenyl)sulfinyl]quinoline(1608477-78-6)

Safety Data

• Hazardous Substances Data: 1608477-78-6(Hazardous Substances Data)

Upstream product

• 870301-30-7 8-chloro-3-[(4-fluorophenyl)sulfanyl]quinoline 
• 611-33-6 8-chloroquinoline 
• 847727-21-3 8-chloro-3-iodo-quinoline 

Downstream Products

• 1608477-67-3 3-[(4-fluorophenyl)sulfinyl]-8-(4-methylpiperazin-1-yl)quinoline 

Relevant articles and documents

Syntheses, radiolabelings, and in vitro evaluations of fluorinated pet radioligands of 5-HT6 serotoninergic receptors

The 5-HT6 receptors are potent therapeutic targets for psychiatric and neurological diseases (schizophrenia, Alzheimers disease, etc.). However, with lack of specific radiopharmaceuticals, their pharmacology is still incomplete and their exploration is limited to animal models. In this context, we have designed a fluorinated PET radiotracer, [18F]2FNQ1P, that possesses a high affinity and selectivity for 5-HT6. In vitro PET autoradiographies in rat brain sections with this radiotracer were in accordance with the 5-HT6 distribution pattern.