1608502-12-0

Basic information

• Product Name: 3-fluoro-4-hydroxyphenyl-4-((3-hydroxybenzyl)(methyl)aminomethyl)phenylmethanone
• Synonyms: 3-fluoro-4-hydroxyphenyl-4-((3-hydroxybenzyl)(methyl)aminomethyl)phenylmethanone
• CAS NO: 1608502-12-0
• Molecular Weight: 365.404
• Mol File: 1608502-12-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-fluoro-4-hydroxyphenyl-4-((3-hydroxybenzyl)(methyl)aminomethyl)phenylmethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-fluoro-4-hydroxyphenyl-4-((3-hydroxybenzyl)(methyl)aminomethyl)phenylmethanone(1608502-12-0)
• EPA Substance Registry System: 3-fluoro-4-hydroxyphenyl-4-((3-hydroxybenzyl)(methyl)aminomethyl)phenylmethanone(1608502-12-0)

Safety Data

• Hazardous Substances Data: 1608502-12-0(Hazardous Substances Data)

Upstream product

• 1147092-76-9 (4-(bromomethyl)phenyl)-(3-fluoro-4-methoxyphenyl)methanone 
• 1147092-74-7 (3-fluoro-4-methoxyphenyl)(p-tolyl)methanone 
• 1608502-21-1 4-bromomethylphenyl-3-fluoro-4-hydroxyphenylmethanone 
• 123926-62-5 N-(3-hydroxybenzyl)methylamine 

Relevant articles and documents

Fluorinated benzophenone derivatives: Balanced multipotent agents for Alzheimer's disease

In an effort to develop multipotent agents against β-secretase (BACE-1) and acetylcholinesterase (AChE), able to counteract intracellular ROS formation as well, the structure of the fluorinated benzophenone 3 served as starting point for the synthesis of a small library of 3-fluoro-4-hydroxy- analogues. Among the series, derivatives 5 and 12, carrying chemically different amino functions, showed a balanced micromolar potency against the selected targets. In particular, compound 12, completely devoid of toxic effects, seems to be a promising lead for obtaining effective anti-AD drug candidates.