160867-97-0 Usage
Uses
Used in Medicinal Chemistry:
Phosphonic acid, [(3S)-3-hydroxy-4-(phenylmethoxy)butyl]-, diethyl ester is used as a building block in the synthesis of complex organic molecules for medicinal chemistry. Its unique structural features, including the hydroxy and phenylmethoxy groups, allow for versatile chemical modifications and the creation of novel bioactive compounds.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, Phosphonic acid, [(3S)-3-hydroxy-4-(phenylmethoxy)butyl]-, diethyl ester serves as a key intermediate in the synthesis of potential drug candidates. Its ability to be modified and incorporated into larger molecular frameworks makes it a valuable asset in the development of new therapeutic agents.
Used in Drug Design:
Phosphonic acid, [(3S)-3-hydroxy-4-(phenylmethoxy)butyl]-, diethyl ester is used as a structural component in drug design, where its specific functional groups can be leveraged to enhance the pharmacological properties of new drugs, such as improving binding affinity to target proteins or modulating the drug's metabolic stability.
Used in Chemical Research:
Phosphonic acid, [(3S)-3-hydroxy-4-(phenylmethoxy)butyl]-, diethyl ester is also utilized in chemical research to explore the reactivity and properties of phosphonic acid derivatives. Understanding its behavior in various chemical reactions can provide insights into the development of new synthetic methods and applications in organic chemistry.
Check Digit Verification of cas no
The CAS Registry Mumber 160867-97-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,6,0,8,6 and 7 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 160867-97:
(8*1)+(7*6)+(6*0)+(5*8)+(4*6)+(3*7)+(2*9)+(1*7)=160
160 % 10 = 0
So 160867-97-0 is a valid CAS Registry Number.
160867-97-0Relevant academic research and scientific papers
Synthesis and biological evaluation of γ-aminophosphonates as potent, subtype-selective sphingosine 1-phosphate receptor agonists and antagonists
Foss Jr., Frank W.,Snyder, Ashley H.,Davis, Michael D.,Rouse, Michael,Okusa, Mark D.,Lynch, Kevin R.,Macdonald, Timothy L.
, p. 663 - 677 (2007/10/03)
The synthesis of N-arylamide phosphonates and related arylether and arylamine analogues provided potent, subtype-selective agonists and antagonists of the five known sphingosine 1-phosphate (S1P) receptors (S1P1-5). To this end, the syntheses of phosphoserine mimetics-selectively protected and optically active phosphonoserines-are described. In vitro binding assays showed that the implementation of phosphonates as phosphate mimetics provided compounds with similar receptor binding affinities as compared to their phosphate precursors. meta-substituted arylamide phosphonates were discovered to be antagonists of the S1P1 and S1P3 receptors. When administered to mice, an antagonist blocked the lymphopenia evoked by a S1P receptor agonist and caused capillary leakage in both lung and kidney.
