16088-60-1

Basic information

• Product Name: [S,(+)]-1-Bromo-2-propanol
• Synonyms: [S,(+)]-1-Bromo-2-propanol
• CAS NO: 16088-60-1
• Molecular Formula: C₃H₇BrO
• Molecular Weight: 138.99108
• Mol File: 16088-60-1.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: [S,(+)]-1-Bromo-2-propanol(CAS DataBase Reference)
• NIST Chemistry Reference: [S,(+)]-1-Bromo-2-propanol(16088-60-1)
• EPA Substance Registry System: [S,(+)]-1-Bromo-2-propanol(16088-60-1)

Safety Data

• Hazardous Substances Data: 16088-60-1(Hazardous Substances Data)

Usage

General Description

[S,(+)]-1-Bromo-2-propanol is a chiral compound with a molecular formula of C3H7BrO. It is a white to light brown solid at room temperature and is often used as a reagent in organic synthesis. This chemical is commonly utilized in the production of pharmaceuticals, dyes, and other organic compounds. Additionally, [S,(+)]-1-Bromo-2-propanol has been shown to have antimicrobial properties, making it useful in the formulation of disinfectants and antiseptics. It is important to note that [S,(+)]-1-Bromo-2-propanol is a hazardous substance and should be handled with care, following proper safety protocols and handling procedures.

Upstream product

• 58-55-9 theophylline 
• 4254-15-3 (S)-1,2-Propanediol 
• 19686-73-8 1-bromo-2-propanol 
• 10035-10-6 hydrogen bromide 
• 75-56-9 methyloxirane 
• 16088-62-3 (S)-Propylene oxide 
• 598-31-2 1-bromoacetone 
• 140886-06-2 ((S)-2-Bromo-1-methyl-ethoxymethoxymethyl)-benzene 
• 137645-39-7 (S)-1-Bromo-2-ethoxymethoxy-propane 
• 64028-83-7 (S)-1-tosyl-2-(1-ethoxyethoxy)propane 
• 72167-64-7 2-((S)-2-Bromo-1-methyl-ethoxy)-tetrahydro-pyran 
• 32464-98-5 (2S)-2-hydroxypropyl 4-methylbenzenesulfonate 

Downstream Products

• 16088-62-3 (S)-Propylene oxide 
• 140886-07-3 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (S)-2-bromo-1-methyl-ethyl ester 

Relevant articles and documents

Synthesis of optically active 2s-, and 7s-methyl-1.6-dioxa-spiro[4.5] decane, the pheromone components of Paravespula vulgaris (L.), from S-ethyl lactate.

(-)-2S, 5RS-1 and (-]-7S, 5S-2 are obtained from S-ethyl lactate 4 and their absolute configuration is thus directly correlated. Accurate enantiomeric compositions of intermediates and products were measured by complexation gas chromatography on nickel-, and manganese-bis-3-heptafluorobutyryl-1R-camphorate, 3. It could be conclusively established that the syntheses proceed with a high degree of preservation of configuration.

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Optical resolution, absolute configuration, and activity of the enantiomers of proxyphylline

The enantiomers of proxyphylline have been separated via their corresponding camphanates. Synthesis of (+)-proxyphylline from theophylline and (S)-propylene oxide derived from (S)-lactic acid established the absolute configuration of the (+) and (-) isomer as S and R, respectively. The activity of the enantiomers as cyclic nucleotide phosphodiesterase inhibitors was tested in human lung tissue homogenate. No differences were found either between the two enantiomers or between the enantiomers and racemic proxyphylline.

Enantiotopic group differentiation and kinetic resolution: Asymmetric reduction of meso-1,3-dihalides

Asymmetric reduction of 1,3-dihalides derived from glycerol occurs with moderate levels of enantiotopic group differentiation. A concomitant kinetic resolution increases the enantiometric purity of the initial product.

Asymmetric Reduction of Trifluoromethyl and Methyl Ketones by Yeast; An Improved Method

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