160882-66-6Relevant academic research and scientific papers
Cerium chloride (III) promoteid nucleophilic addition of organolithium reagents to α-diphenylphosphinoyl ketones. An efficient-method for the synthesis of Horner-Wittig intermediates
Bartoli,Sambri,Marcantoni,Petrini
, p. 8453 - 8456 (1994)
Reaction of α-diphenylphosphinoyl ketones with organolithium reagents, in the presence or anhydrous CeCl3 in THF at -78°C, affords β-hydroxyalkylphosphine oxides in fair to good yields. These are essential to obtain olefins with β-carbon disubs
Synthesis of β-(Diphenylphosphinoyl) Ketones
Bell, Andrew,Davidson, Alan H.,Earnshaw, Chris,Norrish, Howard K.,Torr, Richard S.,et al.
, p. 2879 - 2892 (2007/10/02)
The title compounds may be made by addition of phosphorus nucleophiles (Ph2PO-, Ph2POMgX, Ph2PCl) to enones, by addition of phosphorus-stabilised carbanions to a α-carbonyl cation equivalents (2,3-dichloropropene, epoxides, and α-MeO-ketones) and by oxidation of allyl diphenylphosphine oxides.
