1609-42-3Relevant academic research and scientific papers
A stereoselective synthesis of 1-phenyl-1-buten-3-yne and some 1-heteroaryl analogues
Fossatelli, Marco,Van Der Kerk, Anca C. T. H. M.,Vasilevsky, Sergei F.,Brandsma, Lambert
, p. 4229 - 4232 (2007/10/02)
Z-Enynes, RCH=CHC≡CH (R= phenyl, 2-furyl, 2- and 3-thienyl and 3-pyridyl) can be obtained in ～ 40% overall yields and with a stereoselectivity of> 95% by Pd/Cu-catalyzed cross-coupling of the readily available enyne sulfide HC≡CCH=CHSC2H5
An efficient synthetic method for 1-N,N-dialkylamino-1,3-pentadiynes
Brandsma,Walda,Oosterveld
, p. 73 - 77 (2007/10/02)
The diyne amines CH3C≡CC≡CNR2 (R = CH3 or C2H5) have been synthesized with greater than 50% overall yields starting from 1,4-dichloro-2-butyne, the last step being a base-catalyzed isomerization of HC≡CC≡CCH2NR2.
Investigation in the field of biacetylene derivatives. XXXIX. A new method for the production of alkylthioenynyl alcohols and their transformations with participation of the hydroxyl group
Volkova, K. A.,Levanova, E. P.,Nikol'skaya, A. N.,Volkov, A. N.,Trofimov, B. A.
, p. 1187 - 1191 (2007/10/02)
A simple and effective method was developed for the production of tertiary alkylthioenynyl alcohols from biacetylene, ketones, and thiols in liquid ammonia.A series of their derivatives involving participation of the hydroxyl group were obtained (β-cyanoethyl, trimethylsilyl, and glycidyl ethers and esters, acetals).
