160917-87-3Relevant academic research and scientific papers
Synthesis and evaluation of novel 1,5-benzodiazepines as potent and selective CCK-B ligands. Effect of the substitution of the N-5 phenyl with alkyl groups
Finizia, Gabriella,Donati, Daniele,Oliosi, Beatrice,Tranquillini, Maria Elvira,Ursini, Antonella
, p. 2957 - 2962 (2007/10/03)
The synthesis and biological evaluation of both 3-ureido and 3-carbamate derivatives of 1,5-benzodiazepines bearing bulky alkyl substituents at N-1 and N-5 positions is reported. Their activity as CCK-B receptor antagonists is discussed and compared with the related N-5-phenyl derivatives.
