1609243-43-7Relevant academic research and scientific papers
Biotin-conjugated N-methylisatoic anhydride: A chemical tool for nucleic acid separation by selective 2′-hydroxyl acylation of RNA
Ursuegui,Chivot,Moutin,Burr,Fossey,Cailly,Laayoun,Fabis,Laurent
, p. 5748 - 5751 (2014/05/20)
An isatoic anhydride derivative conjugated to a biotin and a disulfide linker was specifically designed for the separation of nucleic acids. Starting from a DNA-RNA mixture, a selective 2′-hydroxyl acylation of RNAs followed by capture with streptavidin-coated magnetic beads and cleavage of the disulfide led to elution of RNAs. the Partner Organisations 2014.
