1609244-53-2Relevant academic research and scientific papers
A furan coupling the synthetic method of the compound of
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Paragraph 0026-0028, (2017/04/11)
The invention discloses a synthetic method for a furan coupling compound. The synthetic method comprises the following steps: by taking substituted furan as a starting raw material, palladium trifluoroacetate or palladium acetate as a catalyst and oxygen as an oxidant, carrying out one-step synthesis in an organic solvent to obtain a substituted furan coupling product. According to the method, furan coupling directly oxidized by a C-H bond can be realized, the method is simple to operate compared with the traditional method, a substrate application range is wider, the reaction efficiency is higher, and the method is environmentally-friendly, high in yield and high in atom utilization rate.
Palladium-catalyzed C-H homocoupling of furans and thiophenes using oxygen as the oxidant
Li, Na-Na,Zhang, Yan-Lei,Mao, Shuai,Gao, Ya-Ru,Guo, Dong-Dong,Wang, Yong-Qiang
, p. 2732 - 2735 (2014/06/09)
A general and efficient palladium-catalyzed intermolecular direct C-H homocoupling of furans and thiophenes has been developed. The reaction is characterized by using molecular oxygen as the sole oxidant and complete C5-position regioselectivity. Both C2- and C3-substituted furans or thiophenes are appropriate substrates. The approach provides a straightforward, facile, and economical route to bifurans and bithiophenes under mild reaction conditions.
