1609274-48-7Relevant academic research and scientific papers
Efficient, one-pot synthesis of triazolothiadiazinyl-pyrazolone and pyrazolyl-triazolothiadiazine derivatives via multicomponent reaction
Aychiluhim, Tewodros Birhanu,Rao, Vedula Rajeswar
, p. 1422 - 1429 (2014)
A one-pot, multicomponent reaction of 3-(2-bromo acetyl)coumarins, 4-amino-5-hydrazino-4H-[1,2,4]triazole-3-thiol, and different derivatives of ethyl 2-(2-(aryl)hydrazono)-3-oxobutanoates provide an efficient and direct method for the synthesis of 4-(arylydrazono)-3-methyl-1-(6-(coumarin-3-yl)-7H- [1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-3-yl)-1H-pyrazol-5(4H)-ones (4a-h). A similar methodology was also developed for the synthesis of pyrazolyl- triazolothiadiazines (9a-f) using acetyl acetone, 4-amino-5-hydrazino-4H-[1,2,4] triazole-3-thiol, and different derivatives of phenacylbromide. The resulting products were characterized by analytical and spectral data.
