1609457-85-3Relevant academic research and scientific papers
Chiral amide from (1S, 2R)-(+)-norephedrine and furoic acid: An efficient catalyst for asymmetric Reformatsky reaction
Ananthi, Nallamuthu,Velmathi, Sivan
, p. 151 - 158 (2014)
Chiral amide derived from (1S, 2R)-(+)-norephedrine and 2-furoic acid was found to catalyse the asymmetric Reformatsky reaction between prochiral aldehydes and α-bromo ethylacetate with diethylzinc as zinc source. The corresponding chiral β-hydroxy esters were formed in 99% yield with over 80% enantiomeric excess. The presence of air was found to be essential for the effective C-C bond formation. The mechanism for the catalytic reaction was proposed. [Figure not available: see fulltext.]
Chiral amide from (1S, 2R)-(+)-norephedrine and furoic acid: An efficient catalyst for asymmetric Reformatsky reaction
Ananthi, Nallamuthu,Velmathi, Sivan
, p. 151 - 158 (2014/04/03)
Chiral amide derived from (1S, 2R)-(+)-norephedrine and 2-furoic acid was found to catalyse the asymmetric Reformatsky reaction between prochiral aldehydes and α-bromo ethylacetate with diethylzinc as zinc source. The corresponding chiral β-hydroxy esters were formed in 99% yield with over 80% enantiomeric excess. The presence of air was found to be essential for the effective C-C bond formation. The mechanism for the catalytic reaction was proposed. Indian Academy of Sciences.
