160948-27-6Relevant academic research and scientific papers
8-substituted O6-benzylguanine, substituted 6(4)-(benzyloxy)pyrimidine, and related derivatives as inactivators of human O6-alkylguanine-DNA alkyltransferase
Chae,Swenn,Kanugula,Dolan,Pegg,Moschel
, p. 359 - 365 (1995)
Several 8-substituted O6-benzylguanines, 2- and/or 8-substituted 6- (benzyloxy)purines, substituted 6(4)-(benzyloxy)pyrimidines, and a 6- (benzyloxy)-s-triazine were tested for their ability to inactivate the human DNA repair protein, O6/
An improved procedure for the preparation of 8-substituted guanines
Xu, Ming,De Giacomo, Fabio,Paterson, Duncan E.,George, Tesmol G.,Vasella, Andrea
, p. 1452 - 1453 (2007/10/03)
The preparation of 8-substituted guanines using a new phosphorus(III)-mediated cyclisation of 4-acylamino-5-nitrosopyrimidines as the key step is described.
