8-substituted O6-benzylguanine, substituted 6(4)-(benzyloxy)pyrimidine, and related derivatives as inactivators of human O6-alkylguanine-DNA alkyltransferase

DOI: 10.1021/jm00002a018

Source and publish data:

Journal of Medicinal Chemistry p. 359 - 365 (1995)

Update date:2022-08-16

Topics:

Authors:

Chae Chae

Swenn Swenn

Kanugula

Dolan Dolan

Pegg Pegg

Moschel Moschel

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00002a018

Several 8-substituted O⁶-benzylguanines, 2- and/or 8-substituted 6- (benzyloxy)purines, substituted 6(4)-(benzyloxy)pyrimidines, and a 6- (benzyloxy)-s-triazine were tested for their ability to inactivate the human DNA repair protein, O^{6
View More}

Full text of DOI:10.1021/jm00002a018

Products guided by the article

Product name:1H-Purin-2-amine, 8-methyl-6-(phenylmethoxy)-

Cas No:160948-27-6

R&D Labs maybe for 160948-27-6

Suzhou ATL Chemical Co.,ltd

Contact:+86-0512-69209969

Address:Room 317,Lushan Road,Suzhou New District,Jiangsu Province,China.
Jinan Jiaquan Chemical Co.,Ltd

Contact:+86-531-62318366

Address:Room 502 of Yidonghuayuan No.601 Huaxin Road Licheng District Jinan China
Hangzhou GreenCo Science & Technology Co., Ltd.

Contact:86-571-88257303

Address:1713 Room,Jingui Building,Gudun Road,Xihu District,Hangzhou,China
TIANJIN NORTH JINHENG CHEMICAL PLANT.

Contact:0086-22-59952083

Address:DongShigu Country In JiXian TianJin China
Chengdu Pukang Biotechnology Co., Ltd

Contact:+86-28-82550498

Address:No. 558 Rulin Road,Xinjin county,Chengdu city, China

Relevant to this article

Ruthenium chloride catalysed multicomponent reaction for efficient and onepot synthesis of functionalised tetrahydropiperidines at room temperature

Doi:10.3184/174751915X14230617481292
(2015)
The homocoupling reaction of aromatic terminal alkynes by a highly active palladium(II)/AgNO₃ cocatalyst in aqueous media under aerobic conditions

Doi:10.3390/molecules21050606
(2016)
Triphenylene Columnar Liquid Crystals: Excited States and Energy Transfer

Doi:10.1021/j100003a025
(1995)
New terpenoids from Mentha pulegium L. and their antimicrobial activity

Doi:10.1080/14786419.2012.691488
(2013)
Polymer supported ferrocene derivatives. Catalytic hydrosilylation of olefins by supported palladium and platinum complexes

Doi:10.1016/0022-328X(87)85159-8
(1987)
Iodine-Mediated Synthesis of 2-(Methylthio)-4 H-chromen-4-ones and Study of Their Halogenation Reactions

Doi:10.1021/acs.joc.1c00788
(2021)

Article Doi