1609490-95-0Relevant academic research and scientific papers
Asymmetric synthesis of chloroisothreonine derivatives via syn-stereoselective Mannich-type additions across N-sulfinyl-α- chloroimines
Callebaut, Gert,Colpaert, Filip,Nonn, Melinda,Kiss, Lorand,Sillanpaeae, Reijo,Toernroos, Karl W.,Fueloep, Ferenc,De Kimpe, Norbert,Mangelinckx, Sven
, p. 3393 - 3405 (2014/05/20)
Mannich-type reactions of O-Boc glycolic esters across chiral N-sulfinyl-α-chloroaldimines resulted in the efficient and syn-stereoselective synthesis of new γ-chloro-α-hydroxy-β-amino esters (dr > 99 : 1). The α-coordinating ability of the chlorine atom
