1609574-73-3Relevant academic research and scientific papers
Design, synthesis, and evaluation of liver-specific gemcitabine prodrugs for potential treatment of hepatitis C virus infection and hepatocellular carcinoma
Stephenson, Anthony A.,Cao, Sheng,Taggart, David J.,Vyavahare, Vinod P.,Suo, Zucai
, (2021/01/19)
Many successful anti-viral and anti-cancer drugs are nucleoside analogs, which disrupt RNA and/or DNA synthesis. Here, we present liver-specific prodrugs of the chemotherapy drug gemcitabine (2′,2′-difluorodeoxycytidine) for the treatment of hepatitis C v
SUBSTITUTED GEMCITABINE ARYL AMIDE ANALOGS
-
Paragraph 00232; 00233; 00234, (2014/05/24)
In one aspect, the invention relates to substituted gemcitabine aryl amide analogs, derivatives thereof, and related compounds; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating viral
