1609582-63-9Relevant articles and documents
Iron catalyzed β-C(sp2)-H alkylation of enamides
Bertho, Sylvain,Maazaoui, Radhouan,Torun, Damla,Dondasse, Isma?l,Abderrahim, Raoudha,Nicolas, Cyril,Gillaizeau, Isabelle
, p. 17475 - 17482 (2021/10/04)
An attractive and cheap alternative approach was developed for the β-C(sp2)-H (fluoro)alkylation of a range of cyclic and acyclic non-aromatic enamides using either FeCl2as a catalyst or a stoichiometric amount of nontoxic iron powder. This reaction is regioselective and exhibits broad substrate scope and good functional group tolerance.